Women's Health Drugs Flashcards
(43 cards)
What is Endogenous Estrogen used for?
Menopausal hormone therapy (HT)
Female hypogonadism
What is Endogenous Progestin used for?
Menopausal hormone therapy (HT)
Dysfunctional uterine bleeding or amenorrhea
What two cancers can Endogenous Estrogen lead to?
Endometrial hyperplasia → endometrial Cancer
Breast Cancer
What are Selective estrogen receptor modulators (SERMs) used for?
Menopause Hormone Therapy (HT)
What 3 drugs are in the Selective estrogen receptor modulators (SERMs) class?
Tamoxifene
Raloxifene
Bazedoxifene
What do Selective estrogen receptor modulators (SERMs) do?
Agonize estrogen receptors in some cells & block them in others
3 adverse effects of Selective estrogen receptor modulators (SERMs)
Increases endometrial cancer risk
Increases hot flashes
Increases thromboembolism risk
What do Combination oral contraceptives do??
Inhibit ovulation via FSH suppression (estrogen negative feedback)
The follicle cannot mature
What is a “mini-pill”?
Progestin-only oral contraceptive
What does a Progestin-only oral contraceptive do?
Changes cervical secretion
What is the major for a Subdermal etonogestrel implant to be used?
irregular vaginal bleeding
What does Depot medroxyprogesterone acetate do?
inhibition of FSH/LH secretion
Which oral contraceptive has a black box warnign & why?
Depot medroxyprogesterone acetate because of bone loss risk
How does a cooper IUD stop sperm from getting you prego?
Local foreign body rxn & chemical changes toxic to sperm
zaps those fuckers
How does a Levonorgestrel IUD keep you from getting prego?
thickens cervical mucus, inhibit ovulation, alter the endometrium
What is misoprostol used for?
Termination of early intrauterine pregnancy
How does misoprostol work?
blockade of progesterone receptors → expulsion of conceptus
What 3 drugs for follicular maturation?
Clomiphene, Menotropin & Follitropin
Which two follicular maturation drugs require hCG to induce ovulation?
Menotropin & Follitropin
What is hCG & choriogonadotropin alfa used for?
Facilitate ovulation
What are the two big adverse effects of hCG & choriogonadotropin alfa?
Ovarian hyperstimulation syndrome
Ruptured of ovarian cyst
What are the 5 tocolytic drug classes?
B2 agonists
Calcium channel blocker
COX inhibitors
Oxytocin receptor blockers
Magnesium sulfate
What are tocolytic drugs used for?
Suppresses labor that has already started
What B2 agonist drug is a tocolytic?
terbutaline