Wound Care, Abx & Immunisations Flashcards

(54 cards)

1
Q

Wounds types & healing: 6 & 4

A

Traumatic:
- abrasion; epithelialisation & healing under scab
- cut; primary intention
- stab; primary intention
- impalement; primary intention followed by surg intervention
- laceration; secondary intention OR primary after debribement

Iatrogenic:
- incision; epithelialisation
- puncture; primary intention
- acid/alkali burns; primary intention
- split skin removal; primary after surg intervention

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2
Q

Healing types & closures

A

Epithelialisation; epithelium growths over a denuded surface

Primary: edges can be approximated & wound actively closed using techniques

Secondary: edges cannot be approximated & wound needs to heal from bottom thru granulation; left open & wound closes naturally

Tertiary: delayed primary closure due to infection risk, wound closed w techniques after time

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3
Q

HEIDI

A

H- Hx; wound, Pt, environment
E- Examination; Pt’s localised skin, circulation, etc
I- investigation; consider pathology, radiology, haematology or sonography
D- Dx; aetiology/pathophysiology
I- Implement; immed & long term

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4
Q

TIME

A

T- Tissue; non-viable tissue (slough/necrosis), foreign bodies

I- Inflammation; & infection

M- Moisture; imbalances, oedema, temp, pH

E- Edges; rolled, raised, undermined, calloused

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5
Q

Wound Exam general

A
  • location
  • type
  • dimensions
  • tissue types/wound bed
  • exudate type & amount
  • odour
  • wound edges
  • condition of surrounding skin
  • pain
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6
Q

Tissue types & wound bed

A

Epithelialisation: pink, often irregular, at wound edges

Granulation: Red, bumpy, associated w healing wound (reducing size)

Agranular: Red/pink/pale; smooth; not healing (not reducing)

Slough: white-yellow; smooth; soft, sloppy & stringy to tenacious & adherent

Gelatinous slough: firm, gelatinous yellowish coating over the wound

Necrosis: black/tan; hard & dry OR moist & leathery

Hypergranulation: friable; spongy; exceeds over the wound edges

Fat: white-yellow globular

Tendon: white-yellow striated

Bone: white-yellow hard

Others; sutures, mesh, tumour

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7
Q

Clinical Pathway Wounds

A

1- Irrigation & wound cleaning
2- x-ray for foreign bodies PRN
3- primary or delayed primary closure
4- dressing PRN
5- analgesia PRN
6- ADT PRN
7- referral & Pt info

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8
Q

Suture/Staple location & days

A

Face - 3-5
Neck - 3-4
Upper extremity - 7-10
Hand - 10-14
Chest - 7-10
Back - 10-14
Buttocks - 10-14
Legs - 8-10
Foot - 10-14

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9
Q

Pressure injury classifications

A

Stage I- intact skin w unblanchable redness, usually over bony prominence; pigmented skin may be of diff colour than surrounding
Stage II- partial thickness loss of dermis; shallow ulcer w a red-pink bed but no slough; can present as intact/ruptured serum filled blister
Stage III- full thickness tissue loss; subcut fat may be visible, but no bone, muscle or tendon; slough, if present, does not obscure the depth of tissue loss; ulcer edge may be undermined
Stage IV- full-thickness tissue loss w exposed bone/muscle/tendon; may have slough, eschar, undermining, or tunnelling
Unstageable - full-thickness tissue loss & base of ulcer is covered by slough or eschar

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10
Q

Venous Ulcers

A
  • often painful: elevation may help, often worsened by dependency of limb
  • poss Hx of varicose veins, oedema that is worse at the end of the day, haemosiderin staining
  • typically in the gaiter area (lower 1/3 of medial/lateral leg above the malleoli); edge is usually sloping & may be irregular; base maybe be granulating & sloughy; may be heavy exudate
  • surrounding skin: pale scarring, venous dermatitis, or eczema
  • unless comorbid arterial comprise, pulses should be normal

Rx:
Compression therapy: graduated comp therapy improves healing rate; reduces recurrence; must assess ankle brachial pressure index (ABPI) prior to use!
Ulcer dressing: local wound conditions should be optimised for healing; lock away fluid dressing, intact/active for 1 wk, low profile & addresses local wound cond to promote moist healing
Pain management: mod to sever pain can impact ability to tolerate compression; manage pain!
Leg elevation: can aid venous return, reduce pain, reduce oedema; encourage during inactive periods
Exercise: reg gentle exercise (walking, dorsiflexing foot) to maintain calf pump function
Skincare: maintain skin integrity of lower limbs, prevent dryness w bland & simple moisturisers
Pt Ed: about disease process & how manage it

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11
Q

Arterial ulcers

A
  • all Pts must be assessed for PAD (peripheral arterial Dx)
  • often painful, aggrav+ by elevation, but relieved by dependency
  • other features: vasc+ Dx, signs of ischaemia, pallor on elevation, redness on dependency, abnormal ABPI
  • usually on toes, bony prominences, sides of feet or heel; edge may appear punched out; base may be sloughy or covered by eschar; usually minimal exudate

Rx
Ulcer dressing: no specific perfect dressing, select to suit wound
Pain management: very common & may req pain relief prior to dressing changes
Pressure area management: ? Referral to podiatrist to assess feet & footwear; advise Pt to wear well-fitting, closed footwear

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12
Q

Sterile technique

A

Free from microorganisms
Meticulous hand washing, use of sterile field, sterile gloves & dressing & instruments
Sterile to sterile rule!

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13
Q

Clean technique

A

Free of dirt, marks or stains
Meticulous hand washing, maintain a clean environment, using clean gloves & sterile instruments, preventing direct contamination of materials/supplies
NO sterile to sterile rule applies
Appropriate for long-term care, home care, & some clinical settings; for Pt’s not high risk for infection; for Pt’s receiving routine dressings for chronic wounds

Eg; removing staples/sutures

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14
Q

Aseptic technique

A

Free from pathogenic microorganisms
Purposeful prevention of the transfer of organisms from one person to another by keeping the microbe count as low as poss

Egs; wound care, wound closure, insertion of catheters or PEG tubes

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15
Q

No touch technique

A

Method of changing dressings with directly touching the wound or an surface that might come in contact w the wound
Clean gloves w sterile solution/supplies/dressings

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16
Q

LACERATED

A

L-Look: consider time of injury, depth, potential for retained FB & note any functional loss
A-Anaesthetise: choice of drug, max safe vol, ability to explore wound thoroughly
C-Clean: consider best wound decontamination method
E-Explore: satisfy yrself that the wound is suitable for closure
R-Repair: consider best approach to closure & Pt positioning
A-Apply: apply an appropriate dressing
T-Tetanus: check Pt’s status & consider ADT in relation to wound
E-Educate: Pt about ongoing wound care, complications, & removal of sutures
D-Documentation: wound assessment, repair & advice

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17
Q

Everting sutures

A

Simple continuous running: to close multiple layers with one suture; not cut till the end

Continuous locking (blanket): single suture is passed in & out of tissue layers & looped thru free end before passing thru the next - holding the prev one in place

Simple interrupted: each individual stitch is placed, tied & cut in succession

Horizontal mattress: stitches are placed parallel to the wound edges

Vertical mattress: uses deep & superficial bites, each crossing the wound at right angles. Works effectively for the approximation of edges of deep wounds

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18
Q

Skin closure tapes: Adv, Ind & technique

A

Advantages:
- rapid application, little/No Pt discomfort, low cost, no needle injury risk, Allows skin to breathe without moisture collecting under strip, less risk of irritation, no injection req

Indications:
- Minor injuries; lacerations/incisions
- Provide additional tension for wounds closer with Intracutaneous sutures
- Where early replacement of staples/sutures is req to improve cosmetics results
- suitable for thin, fragile or sensitive skin

Technique:
- prepare skin w tincture if benzoic compound to aid adhesion
- place strips with sufficient space between each to allow drainage of fluid
- tell Pt to keep area dry for 72 hrs

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19
Q

Cyanoacrylate glue: Adv, Ind, Technique

A

Adv:
- easy, fast, no pain, no removal/injected anaesthesia req

Ind:
Clean, short <5cm lacs under low tension & w good approximation

Technique:
- hold wound edges in opposition w fingers of non-dominant hand/forceps
- apply thin layer of adhesive across the entire wound, including a margin of at least 5-10mm on either side of wound
- hold for at least 30 secs before removing pressure/tension

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20
Q

Staples: Adv, Ind & Technique

A

Adv:
- ease of use, rapidity, cost-effective, minimal damage to host, low infection risk, off strong closure

Ind:
- scalp lacs that do not req extensive haemostasis
- linear non-facial lacs caused by shear forces (sharp objects)
- can also be used high on trunk

Technique:
- before inserting, it is important to line up wound edges w the centreline indicator on stapler head
- typically use forceps to evert & precisely line up for each staple

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21
Q

Bites & Clenched fist Injs: high risk x5

A
  • wounds w delayed presentation (>8hrs)
  • puncture wounds that cannot be debribed properly
  • wounds; hands, feet, face
  • wounds involving; bones, joints, tendons
  • immunocompromised Pts
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22
Q

Bites & Clenched fist Injs: Abx Mild [common: CC : or MD/T

A

Amoxicillin + Clavulanate
875 + 125mg PO 12 hrly

Pts sensitive to penicillins:
Ciprofloxacin 500mg PO 12 hrly,
PLUS:
Clindamycin 450mg PO 8 hrly
OR:

Metronidazole 400mg PO 12 hrly
PLUS:
Doxycycline 200mg PO 1st dose & 100mg PO daily
OR:
Trimethoprim + Sulfamethoxazole 160 + 800mg PO 12 hrly

Duration: 5/7

23
Q

Bites & Clenched fist Injs: Abx Mod-Sev [M PO + C/C IV]

A

Metronidazole 400mg PO 12 hrly
PLUS:
Ceftriaxone 1gm IV daily
OR:
Cefotaxime 1gm IV 8 hrly

For severe/penetrating wounds, duration:
14/7 & reps combo IV & PO

24
Q

Boils & Carbuncles: Rx & Abx options

A

Usually stand-alone incision & drainage is sufficient
Spreading cellulitis/systemic symptoms:
- incision, draining & Abx
- wound swab prior to Abx Rx

Abx:
Di/flucloxacillin 500mg PO 6 hrly
OR (Pen sens):
Cephalexin

Duration: 5/7

Modify post lab results

25
Cellulitis: risk factors x 9, 3 x notes
- lymphoedema - skin breakdown/site of entry - venous insufficiency - leg oedema - obesity - neutropenia - immunocompromised - chronic renal Dx - cirrhosis Approx 80% cases gram +ve (MRSA, streptococcus progenies/other streptococci) - purulent cellulitis, an abscess may or may not form - systemic signs & findings of leukocytosis & bacteraemia more typical in immunocompromised Pts
26
Cellulitis: man* x 3, Abx; mild, mod, severe
Management: - rest & elevate affected area - incision & drainage of any abscess found - use non-adherent dressings Mild early cellulitis: di/flucloxacillin 500mg PO 6 hrly Pen Sens: Cephalexin 500mg PO 6 hrly Duration 5-10/7 Purulent cell*: Mild - nil Mod - trimethoprim OR doxycycline Severe or not improving after 48hrs: IV flucloxacillin (cephazolin for Pen Sens)
27
Impetigo types: x 2, Aff Vs Remote
Most often in children Crusted or non-bulbous impetigo - yellow crusts & erosions that are irritating/itchy but not painful Bulbous impetigo - irritating blisters that erode rapidly, usually caused by Staph Aureus Affluent comm: 1- staph A 2- streptococcus pyogenes Remote comm: Streptococcus pyogenes is main culprit
28
Impetigo man*: non-remote/remote/recurring
Non-remote Comm: Localised skin sores - mupirocin 2% ointment topically to crusted areas 8hrly 7/7 Multiple skin sores/recurrent - di/flucloxacillin 500mg PO 6hrly up to 10/7 (can be ceased upon resolution) Pen Sens: Cephalexin Remote communities (central & Nth Aus) Benzathine penicillin 900mg IM single dose OR; Trimethoprim + sulfamethoxazole 160 + 800mg PO 12hrly 5/7 OR; Trimethoprim + sulfamethoxazole 320 + 1600mg PO daily 5/7 Recurrent impetigo/resistant organism: Trimethoprim + sulfamethoxazole 160 + 800mg PO 12hrly 5/7 OR; Trimethoprim + sulfamethoxazole 320 + 1600mg PO daily 5/7 - if not responding, modify therapy according to culture results
29
Diabetic foot inf* info: acute Vs chronic, active - assess & R?
Acute infections: staph A or streptococci - if not on recent antimicrobials Chronic infections: polymicrobial; involving gram +ve & -ve, aerobic & anaerobic organisms Active infection: wound cultured recommended to guide therapy Assess vascular supply to affected foot Refer for surg assess/debribement if wound needing investigation
30
Diabetic foot infection: man* ABX; mild-mod Vs severe
Refer for surg assess/debribement Mild - Mod (no osteomyelitis/septic arthritis): Amoxicillin + clavulanate 875 + 125mg PO 12hrly 5/7 OR; Cephalexin 500mg PO 6hrly PLUS Metronidazole 400mg PO 12hrly 5/7 Pen Sens: Ciprofloxacin 500mg PO 12hrly 5/7 PLUS Clindamycin 450mg PO 8hrly 5/7 Severe/systemic toxicity: - septic shock, bacteraemia, necrosis/gangrene, deep ulceration, severe cellulitis, osteomyelitis/septic arthritis Aggressive IV Abx req!!
31
Wound infections: surg site; man* & Abx; mild-mod Vs Severe
Collect swab for gram stain & cultures Minor: often drainage & irrigation w NaCl will resolve issue Mild- Mod w assoc cellulitis: DI/flucloxacillin 500mg PO 6hrly 5/7 (pen Sens: Cephalexin) Gram -ve suspected: Amoxicillin + clavulanate 875 + 125mg PO 12 hrly 5/7 Severe (w systemic features): Flucloxacillin 2gm IV 6hrly Pen Sens: cephazolin IV 8hrly + also Gram -ve: add gentamicin
32
Wound infections: post-traumatics: x 4, Abx; mild Vs severe & prophylactic
- Ensure tetanus up to date - Clean & debribe carefully - Immobilise & elevate - Abx Not routinely req, but prophylactic for contaminated wounds Likely pathogens: Staph A, strep pyogenes, clostridium perfringens, & aerobic gram -ve Penetrating foot injury: pseudomonas aeruginosa is common Management: Abx if >8hrs old or difficult debribement Mild: Amoxicillin + clavulanate 875 + 125mg PO 12hrly 5/7 Pen Sens: Cephalexin 500mg PO 6hrly PLUS metronidazole 400mg PO 12 hrly 5/7 Severe: Cephazolin 2g IV PLUS; metronidazole 500mg IV 12hrly OR; alternatives in ATG
33
Wound infections: non-contaminated
Abx gen not req Yes if; > 8hrs or debridement difficult
34
Wound infections: contaminated/infected Abx
Mild: Amoxicillin + clavulanate 875 + 125mg PO 12hrly Pen Sens: Cephalexin 500mg PO 6hrly PLUS metronidazole 400mg PO 12hrly Severe: Cephalexin 2g IV 8hrly PLUS Metronidazole 500mg IV 12hrly OR ATG alternatives Switch to PO ASAP & totally IV + PO 5-7/7
35
ENT: acute pharyngitis &/or tonsillitis; high risk Pts x 3, & other causes x 2
ATG high risk Pts for Abx - 2-25 yo w sore throat in communities w high incidence of acute rheumatic fever (indig central & Nth Aus, Māori & Pacific Islander peops) - Pts w existing rheumatic heart Dx - Pts w scarlet fever Other causes of acute pharyngitis: Epstein-Barr virus (no Abx req), Peritonsillar abscess, & rarely, diphtheria (req Hosp!)
36
ENT: Acute epiglottis
Relatively rare in children in Aus Adults presenting = urgent management & hosp
37
ENT: otitis externa ; Rx & other x 1
AKA: swimmers ear Most commonly: pseudomonas aeruginous & S Aureus Rx: keep ear dry, refer to GP for management & ear drops Boil: can cause localised otitis externa, Abx can be prescribed
38
ENT: otitis media
Dx difficult as inflammation of middle ear often assoc+ w viral URTIs Rx: referral to GP is wise for assess/manage
39
ENT: pertussis; S&S, Req*, Rx
Caused by bordetella pertussis Typically present w; cough &/or paroxysms of coughing (inspiratory whoop or post-tissue vomiting) Infants <6 months are at greatest risk of morbidity/mortality Notifiable disease in Aus Rx: azithromycin OR trimethoprim + sulfamethoxazole OR clarythromycin Infected individuals req 5/7 Abx before they’re allowed to mingle w others
40
ENT: acute rhinosinusitis: Def x3, Rx x 1;5, ?Abx 3;1
Rapid onset inflam+ of nose & paranasal sinuses w 2 or more additional symptoms: - nasal blockage - nasal discharge - facial pain/pressure - reduction/loss of sense of smell Most common form is Viral, w acute bacterial Inf* a complication Rx: Viral usually resolves within 7-10/7 without Rx OR poss Rx; - adequate & regular oral analgesia (paracetamol, NSAIDs) - saline nasal sprays - topical nasal corticosteroids - topical decongestant for no more than 3 consecutive days - topical ipratropium bromide may lessen rhinorrhoea ?Abx: - Pt’s w symptoms lasting >7/7; w purulent discharge, sinus tenderness, or maxillary toothache OR; Pt has severe symptoms & high fever @ onset lasting >3/7 OR; worsening of symptoms after initial improvement Abx: Amoxicillin + clavulanate OR see ATG
41
Resp: Viruses
SARS - coronavirus from 2002 Avian influenza - influenza A (H5N1) re-emerged in Vietnam 2003 All standard precautions: airborne & droplet & contact COVID 19 - follow current advice Influenza - A, B, or C (A & B more common) w changes in their surface antigens involving H (cell attachment) & N (viral shedding) glycoproteins Assessment: - Hx - age, immunisation status, chronic health cond, immunocompromised, pregnancy, smoking - Onset - incubation period of 1-3 days - S&S - malaise, feverishness, chills, headache, anorexia, nasal discharge, sneezing Severe cases: IV fluids & resp support or vasopressors - those w pneumonia will req Abx
42
Resp: TB: def*; 1* & 2*, Dx, Rx
Aerobic bacteria, usually gram neutral Incubation: from infection to primary lesions 4-12/52 - degree of transmission depends upon No of bacilli in droplets, virulence of bacilli, bacilli exposure to sun or UV, & opportunities for aerosolisation Usually affects lungs, but can affect any organ. Primary Pulmonary TB: initial infection that forms primary lesion & usually resolves spontaneously (10% chance of developing active TB during lifetime) Secondary Pulmonary TB: endogenous reactivation of latent infection, usually localised to upper lobes Dx: usually by S&S, chest X-ray & skin tests Rx: may be protracted w first line & second line therapeutic agents (see ATG)
43
Resp: CAP: Ass x 4, Red Flags x 6, Abx: mild-mod Vs severe
Most commonly Strep pneumoniae, rarer mycoplasma pneumoniae, chlamydia pneumoniae & legionella Haemophilus influenza <5% of CAP, often pre-existing COPD Ass: - Hx & exam - refer for chest X-ray, - O2 sats/blood gases - investigate pathogen: ? Sputum sample, blood cultures, or nose/throat swab Red flags: - RR >30 bpm - BP <90 mmhg - O2 sats <92 % - HR >100 bpm - acute onset confusion - multi-lobar involvement on X-ray Abx: Mild - mod: usually penicillin based Severe - broader spectrum empirical Abx Flow chart on Aus Abx therapeutic guidelines
44
Sepsis: S&S x 4, severe x 3, Man* x 4
1* causes: resp, GU, infra-abdominal, skin & 1* bacteraemia Systemic signs: (2 or more!!) - abnormal temp - >38 or <36 - tachycardia >90 bpm - tachypnoea >20 bpm or PaCO2 <32 mmHg - abnormal WCC - >12000/microL or <4000/microL or >10% immature (band) cells Severe sepsis: - plus organ dysfunction: SBP <90 mmHg or MAP <70 mmHg, elevated lactate, or oliguria Septic shock: - persisting hypotension despite Rx w fluids Management: Haemodynamic resus: - adequate fluid resus before vasopressors or inotropes - norad, adrenaline or vasopressin (?Clin guidelines) - maintain MAP >65 mmHg Supportive measure for perfusion: - ETT & mechanical vent w approp sedation & paralysis Early Abx: - collect approp cultures & commence within 1hr of presentation - choose approp Abx (source, Pt factors, renal function, immunocompromise) - initial course: Broad enough to cover likely pathogens Source control: - control/contain: drainage, debribement, repair
45
Foodborne illness: V Vs B, S&S x 2, Man* x 2 + 1 x 7, Rx x 3
Viral causes: norovirus, rotavirus, astrovirus Bacterial: salmonella, C Diff, C perfringens, campylobacter, yersinia, cryptosporidium, Giardia, E Coli Norovirus: seasonal, winter, usually 24-48 hrs; viral shedding occurs for 24hrs post cessation of symptoms Presentation: - nausea, Vomiting, diarrhoea, abdo cramping - systemic: fever, dehydration & malaise Management: - Dx: comprehensive Hx - most self limiting, though could also be sign of more complex prob - electrolytes & FBC - Pt’s w prolonged symptoms Stool samples for: - watery diarrhoea & signs of hypoVol - bloody diarrhoea - fever >38.5*C - elderly >70 yo - immunocompromised - pregnant women - pt’s w comorbidities (eg; IBS) Rx: - appropriate PPE!! - supportive care: antiemetic or antimotility (loperamide) - maintain hydration: glucose containing solution (eg; gastrolyte) or parenteral dehydration (severe dehydration or continued V or unable to tolerate oral fluids) See AATG for management of specific pathogens
46
Gastroenteritis in Aged Care: S&S x 3, Man* x 3
S&S: - >/= 3 loose bowel motions above baseline in 24hrs - >/= 2 episodes of vomiting over 24hrs - nausea, V, D, abdo pain/tenderness in Pt who has stool based pathogen detected Management - early recognition - infection control practices - Rx & contain at NH
47
UTIs: uncomp Vs comp, S&S x 4 conds, invest* x 2, Man* x 4 cond
Uncomp: healthy person w normal urinary tract Comp: anatomical abnormality, urinary obs or incomplete bladder emptying. Ass: - Hx: risk factors of comp!! - S&S: Lower tract inf (cystitis); dysuria, freq, suprapubic discomfort, macroscopic heamaturia, usually no fever (ex; males w prostatitis) Pyelonephritis; loin pain, fever >38*C, chills & urinary symptoms Ureteric calculus; sever pain IDC Pts: usually no lower symptoms but may have loin pain/fever Investigation: - MSU (midstream urine); reagent strip for leuks, nitrites, haematuria, proteinuria - Urine for culture/sensitivity; Pt’s w recurring Inf, catheterised Pts w S&S, poss pyelonephritis, poss Comp UTI, males, elderly, or Inf* not clinically evident. Management Acute simple cystitis: - trimethoprim 300mg daily for 3/7 (alt: Cephalexin or amoxicillin/clavulanate) Acute Uncomp pyelonephritis: amoxicillin/clavulanate 875/125mg 12 hrly 10/7 (alt: Cephalexin or trimethoprim) Comp UTI - structural: guided by culture & sensitivity Comp UTI - catheter: change catheter if req & Rx if symptomatic as per Comp UTI
48
STIs
- often working alone so assessment limited to Hx & referring Follow local guidelines & refer to STI clinic for follow up Notifiable: - chlamydia, gonorrhoea & syphilis (there are more)
49
HIV
Human immunodeficiency virus: makes peops immunocompromised AIDS: acq imm deficiency syndrome; sever life threatening consequence of HIV - often result of damage to immune Sys Refer** if concerned, GPs have broad guidelines around this.
50
HSV Type 1 & 2: Ass x 4, man* x 2
Viruses that cause oral & genital infections - treatable w antivirals Ass: - most are subclinical, so difficult - symptomatic HSV 1 - pro-labial lesions - symptomatic HSV 2 - genital herpes - HSV encephalitis: acute onset fever & neuro symptoms; hemiparesis, cranial nerve abnormalities, ataxia, focal seizures & altered GCS/behaviour - comprehensive pathology & radiology req for formal Dx Management: - healthy Pts w 1* inf - oral acyclovir (or similar) 7-10/7 - HSV encephalitis- IV acyclovir
51
Varicella: Ass x 4, Comp x 3 & Manage x 3
Ass: - febrile w vesicular rash - assoc non-specific symptoms; headache, malaise, loss of appetite - most inf* self limiting - complications; extreme age/immunocompromised Complications: - bacterial superinfections of skin lesions leading to Nec Fasc - some children may develop visceral involvement & CNS complications - pneumonitis may develop, esp pregnant women Management: - supportive care only for most healthy - acyclovir (& similar) decrease lesions & shorten course of started within 24hrs of rash onset (also considered for higher risk Pts) - secondary skin inf* likely caused by group A Strep - Rx w first-gen cephalosporin
52
Herpes Zoster: Ass x 4, man* x 5
Herpes Zoster Ass: - prodrome of malaise, headache & photophobia - S&S; pain, itching & paraesthesias in one or more dermatome - development of macropapular rash that becomes vesicular; eruption does not cross the midline - HZ opthalmicus can cause blindness!! Management: - antivirals may hasten resolution of many S&S, but Not post-herpatic neuralgia - commence AVs within 72hrs of rash onset: any time for immunocompromised Pts - more severe disease: ? IV AVs - consider opioids for pain - consider corticosteroids for pain
53
Tetanus: contraind x 2, precautions x 2, & side effects x 2, dose
Tetanus: - caused by clostridium tetanus - spores found in soil & can enter wounds - acute, often fatal, disease - neurotoxin that acts on CNS & causes muscle rigidity & spasms - usually an incubation period of 3-21 days - most deaths in >70yo, esp women, & may be assoc w minor injury Immunisation: - DTP vax only in Aus - antitoxin produced dose not prevent future infection but protects body from toxin produced by inf* Indications: Tetanus prone wounds Contraindications: - known, severe allergic reaction/hypersensitivity - Pts <10yo req reduced dose Precautions: - current acute illness - pregnancy Side effects: - pain at injection sight - less common; headache, lethargy, malaise, myalgia, fever, bacterial neuritis (spec; brachial neuritis - not common) Preg Cat: A Admin: Adults: 0.5mL IMI single dose only Paeds (>/= 10yo): as above
54
Influenza: contraind x 4, precautions x 1, side effects x 4, & Clin prac points x 5, dose
Influenza: - virus types A & B affect humans - surface antigens: haemagglutinin (H) & neuraminidase (N) - aerosolised or direct contact w secretions Severe disease: - advanced age - lack of prev exposure - greater virulence of strain - chronic Dx; heart/lung Dx, renal Dx, diabetes - pregnancy, immunocompromised, smoking Vax: Usually contain 2 x A & 1 x B strains Contraindications: Severe allergic reaction or hypersensitivity to; - seasonal influenza vax - gentamicin, neomycin, or polymycin Abx - polysorbate 80, octoxinol 9 or formaldehyde (components of vax) - chicken products (eggs, feathers) Current immunosuppressant Thx Pregnancy/lactation Current episode of febrile illness - >38.5 temp Hx G-B syndrome Precautions: - current warfarin, theophylline (asthma& COPD), phenytoin or phenobarbitone (anticonvulsants) Thx Side effects: - allergic reaction - discomfort, redness, swelling at injection site - influenza-like illness - headache Clinic Prac Points: - immunisation usually takes 2 wks post-admin to occur - must be administered yearly to maintain immunity - storage - cold chain must be maintained - be prepared for adverse events - observe for min 15mins post admin Preg Cat: B2 Admin: Adults - 0.5mL IMI single dose only (dependant on vax)