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Oral Physio > Wound Healing > Flashcards

Wound Healing Flashcards

1
Q

Wound healing is an intericate coordinate series of processes that involve?

And it leadds to the release of?

A

Cellular and subcellular response
Cytokines and growth factors

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2
Q

Acute wounds has?

A

Surgical traumatic, pathological, ischemic causes

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3
Q

Intentionally created in the operating room environment

A

Surgical wounds

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4
Q

caused by blunt or penetrating trauma result in tissue laceration, abrasion, or even tissue avulsion

A

Traumatic injuries

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5
Q

When the tissue’s normal healing process experiences a disruption or delay, a ______ wound forms.

A

chronic

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6
Q

Begins at the time of injury and lasts for 3 to 5 days.

A

INFLAMMATORY PHASE

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7
Q

Normal wound healing results in tissue regeneration and takes place in three separate but overlapping phases

A

Inflammation, proliferation, remodelling

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8
Q

Inflammatory phase begins at? And last for?

A

time of injury and lasts for 3 to 5 days.

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9
Q

What initiates the process of inflammatory phase?

A

Vasoconstriction

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10
Q

_____,_____ cause small blood vessels to constrict for initial hemostasis.

A

catecholamines and prostaglandins

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11
Q

When platelets adhere to the exposed subendothelial collagen of injured vessels with the aid of von Willebrand factor, they degranulate, releasing

A

adenosine triphosphate, serotonin, prostaglandins, and thromboxane A2.

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12
Q

Fourth or fifth day and last 2 to 3 weeks

A

Proliferative phase

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13
Q

Characterized by the ingrowth and proliferation of granulation tissue within the wound

A

PROLIFERATIVE PHASE

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14
Q

Proliferative phase start at____ day and last ___ to___ weeks

A

Fourthh or fifth, 2-3 weeks

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15
Q

Actively produce proteoglycans and collagen, with force, stress, strain, and motion directing the collagen and proteoglycan alignment

A

Fibroplasia

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16
Q

Crucial part of healing

new vasculature is required for the influx of oxygen and nutrients and the removal of metabolic waste products

A

Angiogenesis

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17
Q

Epithelialization three phases

A

Epithelial migration, proliferation and differentiation

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18
Q

Tissue remodeling finalizes the wound healing process

Characterized by an increase in wound tensile strength related to increased collagen production and breakdown

A

MATURATION

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19
Q

Begins after the third week and usually lasts 6 to 12 months

A

MATURATION

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20
Q

Maturation phase begins at the _____ week and usually last ___ to___ months

A

Third week, 6-12 months

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21
Q

Abnormal Soft Tissue Healing (Repair)

Clinically similar, they differ in their formative timeline and boundaries

A

KELOIDS AND HYPERTROPHIC SCARS

22
Q

TYPES OF WOUND HEALING

A

PRIMARY INTENTION SECONDARY INTENTION TERTIARY INTENTION

23
Q

Healing by ________ occurs in wounds with dermal edges that are close together (e.g a scalpel incision).

It is usually faster than by secondary intention, and occurs in four stages

A

primary intention

24
Q

Healing by _______ occurs when the sides of the wound are not opposed, therefore healing must occur from the bottom of the wound upwards.

A

secondary intention

25
Q

An uncommon complication from wound healing (particularly in people with darker skin), are keloid scars, whereby there is excessive collagen production, leading to extensive scarring. This can occur in both primary and secondary intention healing.

A

SECONDARY HEALING INTENTION

26
Q

is delayed primary wound healing after 4–6 days. This occurs when the process of secondary intention is intentionally interrupted and the wound is mechanically closed.

A

TERTIARY HEALING INTENTION

27
Q

the action of platelets and cytokines forms a haematoma and causes vasoconstriction, limiting blood loss at the affected area

A

Haemostasis

28
Q

a cellular inflammatory response acts to remove any cell debris and pathogens present

A

Inflammation

29
Q

cytokines released by inflammatory cells drive the proliferation of the fibroblasts and the formation of granulation tissue

A

Proliferation

30
Q

collagen fibres are deposited within the wound to provide strength in the region, with the fibroblasts subsequently undergoing apoptosis

A

Remodelling

31
Q

located between the ramus of the mandible and the ear, and deep to the muscles in that area

A

Parotid

32
Q

located in the posterior area of the floor of the mouth, beneath the mylohyoid muscle

A

Submandibular

33
Q

located in the anterior area of the floor of the mouth, above the mylohyoid muscle

A

Sublingual

34
Q

MAJOR SALIVARY GLANDS

A

Parotid,submandibular,sublingual

35
Q

The parotid gland secretes saliva into the oral cavity via

A

Stensens duct

36
Q

The submandibular gland secretes saliva into the floor of the mouth via

A

Whartons duct

37
Q

The sublingual gland secretes saliva into the floor of the mouth via

A

Bartholin’s duct

38
Q

Largest salivary gland

A

Parotid gland

39
Q

Situated in the posterior part of the floor of the mouth, adjacent to the medial aspect of the mandible and wrapping around the posterior border of the mylohyoid muscle

A

Submandibular gland

40
Q

Submandibular blood supply and parasympathetic nerve supply?

A

Facial and lingual arteries
CN VII- vestibulocochlear nerve

41
Q

Smallest of the paired major salivary glands

Located in the anterior part of the floor of the mouth between the mucosa and the mylohyoid muscle

A

SUBLINGUAL GLAND

42
Q

Sublingual. Blood supply and parasympathetic innervation?

A

Sublingual and submental A.
CNII-facial nerve

43
Q

The major salivary gland begin development in the embryo at around the ___

A

seventh week

44
Q

The parotid glands begin to develop at ___ to___ week of embryonic life

A

4 to 6

45
Q

The submandibular glands begin to develop at ___ weeks

A

6 weeks

46
Q

The Sublingual and minor salivary glands at ___ to ___ weeks

A

8-12 weeks

47
Q

difficulty in eating, speaking, and swallowing, prone to mucosal infections and rampant caries

A

Xerostomia

48
Q

Complex fluid

A

SALIVA

49
Q

SECRETORY CELLS

A

Serous cells, Mucous cells

50
Q

Serous cells:

A

Proteins and glycoproteins
Enzymatic, antimicrobial, calcium binding activities

51
Q

Mucous cells

A

Mucin (apomucin)
Lubricate and form a barrier on surfaces and to bind and aggregate microorganism

52
Q

Parotid gland blood supply and parasympathetic nerve supply?

A

External carotid A,
Glossopharyngeal N

Oral Physio (3 decks)

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