XIX - Female Genital System and the Breast Flashcards Preview

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Flashcards in XIX - Female Genital System and the Breast Deck (173)
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31

This type of H. mole shows hydropic swelling of chorionic villi and virtual absence of vascularization of villi. No fetal parts seen.

Complete mole (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 736

32

This type of H. mole shows villous edema that involves only some of the villi and the trophoblastic proliferation is focal and slight, with characteristic irregular scalloped margin. Fetal parts/embryo may be seen.

Partial mole(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 736

33

These are complete moles that are more invasive locally but do not metastasize. Microscopically, the epithelium of the villi is marked by hyperplastic and atypical changes, with proliferation of both cuboidal and syncytial components.

Invasive Mole (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 736

34

Appear as very hemorrhagic, necrotic masses within the uterus. The tumor is purely epithelial, composed of anaplastic cuboidal cytotrophoblast and syncytiotrophoblast, chorionic villi are not formed. High propensity for metastasis.

Choriocarcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 737

35

Term used to describe hyperplasia that cytologically resemble lobular carcinoma in situ, but the cells do not fill or distend more than 50% of the acini within a lobule.

Atypical lobular hyperplasia (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 739

36

The lumen of the ducts, ductules, or lobules of the breast is filled with a heterogeneous population of cells of different morphologies. Irregular slit-like fenestrations are prominent at the periphery.

Epithelial Hyperplasia (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 739

37

These lesions are characterized by proliferation of lining epithelial cells and myoepithelial cells in small ducts and ductules, yielding masses of small gland patterns within a fibrous stroma. The acini are arranged in a swirling pattern, and the outer border is usually well circumscribed.

Sclerosing Adenosis (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 741

38

A nonbacterial chronic inflammation of the breast associated with inspissation of breast secretions in the main excretory ducts.

Mammary duct ectasia (periductal or plasma cell mastitis) (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 742

39

The lesion is small, often tender, rarely more than 2 cm in diameter, and sharply localized, with a central focus of necrotic fat cells surrounded by neutrophils and lipid-filled macrophages. Caused by some antecedent trauma to the breast.

Traumatic fat necrosis (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 742

40

Small lobulated and cystic lesion of the breast that may grow rapidly. Exhibit "leaflike" clefts and slits on gross section.

Phyllodes Tumor (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 743

41

A neoplastic papillary growth within a duct, usually solitary and less than 1 cm in diameter, consisting of delicate, branching growths within a dilated duct or cyst.

Intraductal Papilloma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 743

42

A type of noninvasive carcinoma of the breast that tends to fill, distort, and unfold involved lobules and thus appears to involve ductlike spaces.

Ductal Carcinoma in Situ(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 745

43

A type of noninvasive carcinoma of the breast expands but does not alter the underlying lobular architecture. Cells are monomorphic with bland, round nuclei and occur in loosely cohesive clusters in ducts and lobules. Tend to be bilateral, and increases risk for development of breast CA.

Lobar Carcinoma in Situ(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 746

44

Caused by the extension of DCIS up to the lactiferous ducts and into the contiguous skin of the nipple.

Paget disease of the nipple (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 746

45

This type of cancer produces a desmoplastic response, replacing normal breast fat and forms a hard, palpable mass. Advanced cancers may cause dimpling of the skin, retraction of the nipple, or fixation to the chest wall.

Invasive ductal carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

46

Breast cancer defined by the clinical presentation of an enlarged, swollen, erythematous breast, usually without a palpable mass. The blockage of numerous dermal lymphatic spaces by carcinoma results in the clinical appearance (e.g peau d' orange)

Inflammatory carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

47

Breast cancer which consists of cells morphologically identical to the cells of LCIS. Occasionally they surround cancerous or normal-appearing acini or ducts, creating a so-called "bull's-eye pattern."

Invasive lobular carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

48

A rare subtype of carcinoma consisting of sheets of large anaplastic cells with pushing, well-circumscribed borders, with a pronounced lymphoplasmacytic infiltrate.

Medullary carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

49

A rare subtype of carcinoma which appear grossly as a soft and gelatinous mass which abundant quantities of extracellular mucin that dissects into the surrounding stroma.

Colloid (mucinous) carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

50

Usually present as irregular mammographic densities. Microscopically, the carcinomas consist of well-formed tubules with low-grade nuclei. Lymph node metastases are rare, and prognosis is excellent.

Tubular carcinomas (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

51

Grossly, appears as a button-like, subareolar swelling. in bilateral breasts of males.

Gynecomastia (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 750

52

Large, multilocular tumors of the ovaries, without psammoma bodies. Composed of mucin-producing epithelial cells.

Mucinous Tumors (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 731

53

Metastasis of mucinous tumor of the gastrointestinal tract to the ovaries is called?

Krukenberg tumor(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 731

54

Unilateral ovarian tumor composed of sheets or cords of large cleared cells separated by scant fibrous strands. Stroma may contain lymphocytes and occasional granuloma. Usually occur on the 2nd-3rd decade of life.

Dysgerminoma(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 732

55

Unilateral ovarian tumor which occur during the 1st 3 decades of life. Characterized by small, hemorrhagic focus with syncitiothrophoblast and cytotrophoblast. Metastasize early.

Choriocarcinoma(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 732

56

Sex cord tumor characterized by solid gray fibrous cells to yellow (lipid-laden) plump thecal cells. Most hormonally inactive.

Thecoma-fibroma tumor(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 732

57

Sex cord tumor seen as small, gray to yellow-brown, and solid lesions. May resemble development of testis with tubules, or cords and plump pink Sertoli cells. May be masculinizing or defeminizing.

Sertoli-Leydig cell tumor(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 732

58

On transection, filled with sebaceous secretion and matted hair, bonw and cartilage, nests of bronchial or gastrointestinal epithelium, and other recognizable lines of development are also present.

Benign (Mature) Cystic Teratomas / Dermoid Cyst(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 733

59

Microscopically, the distinguishing feature is a variety of immature or barely recognizable areas of differentiation toward cartilage, bone, muscle, nerve, and other structures. Found early in life.

Immature Malignant Teratomas (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 733

60

Appear as very hemorrhagic, necrotic masses within the uterus. The tumor is purely epithelial, composed of anaplastic cuboidal cytotrophoblast and syncytiotrophoblast, chorionic villi are not formed. High propensity for metastasis.

Choriocarcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 737