XV - The Oral Cavity and the GI Tract Flashcards Preview

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Flashcards in XV - The Oral Cavity and the GI Tract Deck (141)
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61

A malignancy in the ovary that metastasized from a gastric adenocarcinoma.

Krukenberg tumor(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 599

62

Complete failure of development of the intestinal lumen.

Atresia(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 600

63

Narrowing of the intestinal lumen with incomplete obstruction.

Stenosis(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 600

64

Most common intestinal anomaly which results from the failure of involution of the omphalomesenteric duct, leaving a persistent blind-ended tubular protrusion as long as 5-6cm.

Meckel diverticulum(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 600

65

A congenital defect of the periumbillical abdominal musculature that creates a membranous sac, into which intestines herniate.

Omphalocoele(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 600

66

Extrusion of the intestines caused by lack of formation of a portion of the abdominal wall.

Gastroschisis(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 600

67

Condition that prevents the intestines from assuming their normal intra-abdominal positions.

Malrotation(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 600

68

Critical lesion in the development of Hirschprung disease.

Lack of ganglion cells in the muscle wall and submuco lf the affected segment.(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 601

69

Ischemic lesion of the intestines which extends only up to the muscularis mucosae.

Mucosal infarction(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 601

70

Ischemic lesion of the intestines involving the mucosa and submucosa, sparing the muscular wall.

Mural infarction(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 601

71

Ischemic lesion of the intestines involving all of the visceral layers.

Transmural infarct(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 601

72

Most common cause of transmural infarction of the intestines.

Acute occlusion of a major mesenteri artery(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 602

73

Development of sudden abdominal pain out of proportion to the physical signs. Sometimes accomplanied by bloody diarrhea. May progress to shock and vascular collapse within hours.

Ischemic bowel injury(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 602

74

A weakness or defect in the wall of the peritoneal cavity, which permits protrusion of a pouch-like serosa lined sac of peritoneum.

Hernia(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 603

75

A blind pouch that communicates with the lumen of the gut. Histologically describes as small, flask-like or spherical outpouchings, usually 0.5 to 1 cm diameter.

Diverticula(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 602

76

Telescoping of a proximal segment of a bowel into the immediately distal segment

Intussusception(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 604

77

Refers to twisting of a loop of bowel or other structure about its base of attachment, constricting venous outflow and sometimes the arterial supply.

Volvulus(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 604

78

Characterized by transmural inflammation of the bowel, associated with noncaseating granulomas and fistula formation. Intestinal walls are rubbery and thick. (+) skip lesions, creeping fat mesentery

Chron's disease(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 613

79

An ulceroinflammatory disease of the colon which is limited to the mucosa and submucosa. No granulomas, no skip lesions. High risk of carcinoma development.

Ulcerative colitis(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 614

80

Small, nipple-like, hemispherical, smooth protrusions of the intestinal mucosa. May occur singly or multiple.contains abundant crypts luned by well-differentiated goblet or epithelial cells separated by scant lamina propria.

Hyperplastic polyps(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 617

81

Hamartomatous proliferations mainly of lamina propria, enclosing widely spaced, dilated cystic glands. Occur most frequently in children younger than 5 years old.

Juvenile polyps(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 618

82

Most common type of intestinal adenoma, which are tubular glands with slender stalks and raspberry-like heads composed pf neoplastic epithelium forming branching glands lined by tall, hyperchromatic cells.

Tubular adenomas(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 618

83

Larger, more ominous intestinal epithelial polyp. Tends to occur in older persons at the rectum or rectosigmoid. Sessile, velvety and cauliflower-like mass projecting 1-3cm above the surrounding mucosa. Frondlike villiform extensions covered by dysplastic columnar epithelium.

Villous adenomas(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 618

84

Composed of broad mix of tubular and villous areas, an intermediated between tubular and villous lesions.

Tubulovillous adenomas(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 618

85

Uncommon autosomal dominant disorder with propensity for malignant transformation. Patients with this disease typically develop 500 to 2500 colonic adenomas that carpet the mucosal surface.

Familial adenomatous polyposis(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 619

86

Uncommon hamartomatous polyps associated with melanotic mucosal and cutaneous pigmentation. Caused by germ-line mutations in LKB1 gene.

Peutz-Jeghers syndrome(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 619

87

Polypoid, exophytic masses that extend along the wall of capacious cecum and ascending colon. Symptoms of fatigue, weakness and iron deficiency anemia.

Right sided colorectal carcinoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 623

88

Annular, encircling lesions, "napkin-ring" constrictions of the bowel and narrowing of the lumen. Symptoms pf occult bleeding, changes in bowel habit or crampy left lower quadrant discomfort.

Left-sided colorectal carcinoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 623

89

Tumor of the small intestines, showing spindle cells with elongated nuclei with fine chromatin and eosinophilic fibrillar cytoplasm. (+) c-KIT gene mutation

Gastrointestinal stromal tumors (GIST)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 628

90

Most common site of carcinoid tumors.

Appendix(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 627