Flashcards in XV - The Oral Cavity and the GI Tract Deck (224)
Tumors arising from endocrine cells along the GIT. Solid, yellow-tan appearance on transection. Neoplastic cells have a scant, pink granular cytoplasm and a round-to-oval stippled nucleus.
Carcinoid tumors(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 627
What is the most common ectopic tissue rests seen in the esophagus?
Ectopic Gastric Mucosa seen in the upper third of the esophagus (TOPNOTCH)
What is the most common location of Mallory Weiss Tears?
Esophagogastric junction or in the proximal gastric (TOPNOTCH)
Definitive diagnosis of Barret Esophagus is made when what type of cells is seen in the columnar mucosa?
Intestinal Goblet Cells(TOPNOTCH)
What type of esophagitis presents with punched out linear ulcers with nuclear inclusions seen in degenerating epithelial cells?
What type of esophagitis presents with linear ulcerations of the esophageal mucosa with histologic findings of intranuclear and cytoplasmic inclusions?
98% of Peptic Ulcers are located in what part of the GIT?
First portion of the anterior part of the duodenum(TOPNOTCH)
What is the most common location of gastric ulcer?
Lesser curvature (TOPNOTCH)
What is the most common location of gastric carcinoma is?
Pylorus and antrum > Cardia > body and fundus(TOPNOTCH)
What is the morphologic feature of gastric carcinoma that has the greatest impact on the clinical outcome?
Depth of invasion(TOPNOTCH)
What is the most common primary source of gastric metastasis?
What is the usual organism that cause spontaneous bacterial peritonitis in patients with nephrotic syndrome?
In bacterial peritonitis, approximately how many hours from the time of initiation before there is loss of the gray, glistening quality of the peritoneal surface and it becomes dull and lusterless?
What is the histologic criterion for the diagnosis of acute appendicitis?
Presence of neutrophilic infiltration of the muscularis propria.(TOPNOTCH)
What is the most important prognostic indicator of colorectal carcinoma?
The extent of the tumor at the time of diagnosis or the stage(TOPNOTCH)
Morphology: a type of adenoma that has frondlike villiform extensions of the mucosa, covered by dysplastic, sometimes very disorderly columnar epithelium
These structures represent islands of inflamed regenerating mucosa surrounded by ulceration
Inflammatory or pseudopolyps(TOPNOTCH)
Most adenomas are seen in what part of the GIT?
Ampulla of Vater(TOPNOTCH)
Most tubular adenomas are found in what part of the GIT?
Gross morphology: small, flask like or spherical outpouchings, usually 0.5 to 1 cm and located in the sigmoid colon
Morphology: thin wall composed of flattened or atrophic mucosa, compressed submucosa, and attenuated or totally absent muscularis propria.
What are the two most important factors in the genesis of colonic diverticula?
Focal weakness in the colonic wall and increased intraluminal pressure(TOPNOTCH)
What is the most common site of angiodysplasia?
Morphology: these are tortuous dilations of submucosal and mucosal blood vessels
What area of the GIT is at greatest risk of ischemic injury?
Morphology: diffuse active inflammation with crypt abscess and glandular architectural distortion
What is the earliest lesion seen in Crohn Disease?
Focal neutrophilic infiltration into the epithelial layer, particularly overlying mucosal lymphoid aggregates(TOPNOTCH)
What is the hallmark of inflammatory bowel disease, both CD and UC?
Chronic mucosal damage(TOPNOTCH)
Gross morphology: narrowing of lumen, bowel wall thickening, serosal extension of mesenteric fat, and linear ulceration of the mucosal surface