XV - The Oral Cavity and the GI Tract Flashcards Preview

Pathology > XV - The Oral Cavity and the GI Tract > Flashcards

Flashcards in XV - The Oral Cavity and the GI Tract Deck (224)
Loading flashcards...
121

Gross morphology: intestinal wall is rubbery and thick, as a consequence of edema, inflammation, fibrosis and hypertrophy of the muscularis propria

Crohn disease(TOPNOTCH)

122

Morphology: small intestinal mucosa laden with distended macrophages in the lamina propria which are PAS positive and contains numerous bacilli and diastase resistant granules

Whipple disease(TOPNOTCH)

123

Intestinal lipodystrophy is associated with what disease entity?

Whipple disase(TOPNOTCH)

124

Morphology: diffuse severe atrophy and blunting of villi, with a chronic inflammatory infiltrate in the lamina propria

Celiac disease(TOPNOTCH)

125

Morphology: focal crypt cell necrosis or apoptosis with minimal to absent inflammatory cell response in the lamina propria

Acute GVHD(TOPNOTCH)

126

Morphology: marked blunting of the small intestinal villi with a mixed inflammatory infiltrate resembling the atrophic stage of celiac disease

Giardiasis(TOPNOTCH)

127

Morphology: superficial erosion of the mucosa and an adherent pseudomembrane of fibrin, mucus, and inflammatory debris

Pseudomembranous colitis(TOPNOTCH)

128

Morphology: small intestinal mucosa usually exhibits modestly shortened villi and infiltration of the lamina propria by lymphocytes

Viral gastroenteritis(TOPNOTCH)

129

What virus affecting the GIT can produce a flat mucosa resembling celiac sprue?

Rotavirus(TOPNOTCH)

130

Morphology: characterized by the absence of ganglion cells and ganglia in the muscle wall and submucosa of the affected segment

Hirchsprung Disease/Congenital Aganglionic Megacolon(TOPNOTCH)

131

Stercoral ulcers are seen in what disease entity?

Hirchsprung Disease/Congenital Aganglionic Megacolon(TOPNOTCH)

132

The majority of these tumors are positive for c-KIT (CD 117)

Gastrointestinal Stromal Tumor(TOPNOTCH)

133

What is the most common site of gastric carcinoma?

Pylorus and antrum 50%-60%(TOPNOTCH)

134

What is the most favored site of gastric carcinoma?

lesser curvature of the anthropyloric region(TOPNOTCH)

135

What is the most common type of gastric polyp?

Hyperplastic polyp(TOPNOTCH)

136

In gastritis, histologically, what signifies an active inflammation?

Presence of neutrophils above the basement membrane.(TOPNOTCH)

137

H. pylori infection in duodenal ulcers is present in about how many percent of patients?

Virtually ALL (70% in patients with gastric ulcer(TOPNOTCH)

138

Most common site of diverticulitis

Sigmoid colon (TOPNOTCH) Robbins Pathologic Basis of Disease, 9th ed., p. 803

139

A 10 y/o male presented with recurrent painless rectal bleeding with no other associated symptoms. PE findings were unremarkable. The abdomen was soft, non tender, with no palpable mass. What is the clinical impression?

Meckel Diverticulum (TOPNOTCH)

140

Most common site of Meckel Diverticulum

Antimesenteric border of ileum (TOPNOTCH)

141

True or False. Meckel diverticulum is a true diverticulum

True (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 751

142

Most common site of acquired diverticula.

Sigmoid colon (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 751

143

The most common true diverticulum

Meckel Diverticulum (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 751

144

A 3 week old male infant presented to the ER due to vomiting. Mother denies bilious or bloody emesis. Mother states he is always hungry and vomits after nearly every bottle. PE reveals firm, ovoid, 2 cm abdominal mass. What is the most likely diagnosis?

Pyloric stenosis (TOPNTOCH)

145

Pathology of Pyloric stenosis

Hyperplasia of pyloric muscularis propria (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 751

146

Pyloric is more common in male or female?

3-5x more common in male (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 751

147

A 3-day-old infant presented with emesis and failure to pass meconium for the first 36 hours. PE revealed a moderately distended abdomen. Bowel sound are active. No organs or abdominal masses were palpated. Anus was patent. What is the clinical impression?

Hirchsprung's Disease (TOPNOTCH)

148

Most important diagnostic test in Hirchsprung Disease

Rectal biopsy (TOPNOTCH)

149

Histologic findings in Hirchsprung Disease

Absence of ganglion cells in the submucosal and myenteric plexuses.(and hypertrophic extrinsic nerve fibers) (TOPNOTCH)

150

Typically presentes with failure to pass mecondium in the immediate postnatal period, followed by obstruction or constipation, often with visible ineffective peristalsis, progressing to abdominal distention and bilious vomiting.

Hirchsprung's Disease(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 752