XV - The Oral Cavity and the GI Tract Flashcards Preview

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Flashcards in XV - The Oral Cavity and the GI Tract Deck (224)
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181

Most frequent etiology of noninfectious chronic gastritis

Autoimmmune gastritis(TOPNOTCH)Robbins Basic Pathology, 9th Ed p. 768

182

Characterized by irregular enlargement of gastric rugae associated with excessive secretion of TFG-alpha.

Menetrier disease(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 768

183

Syndrome most commonly found in the small intestine or pancreas, caused by gastrin-secreting tumors; most remarkable feature is doubling of oxyntic mucosal thickness

Zollinger-Ellison Syndrome(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 769

184

Most common site of gastric adenoma in the stomach

Antrum(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 770

185

Most common malignancy of the stomach

Adenocarcinoma(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 771

186

Most common type of cancer the predominates in high-risk areas and develops from flat dysplasia and adenomas

Intestinal-type gastric cancer(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 772

187

Most common site of extranodal lymphoma

Stomach(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 773

188

Most common inducer of MALToma in the stomach

H. pylori(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 773

189

GI Tumor characterized by cutaneous flushing, sweating, bronchospasm, colicky abdominal pain, diarrhea, and right-sided cardiac valvular fibrosis.

Carcinoid tumor(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 774

190

The most common mesenchymal tumor of the abdomen

GI stromal tumor(GIST) tumor(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 775

191

The most important prognostic factor for GI Carcinoid tumor

Location(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 775

192

Most common site of GIST

Stomach(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 777

193

Most frequent cause of intestinal obstruction

Hernias(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 777

194

Most common sites of ischemic bowel disease

Splenic flexure, sigmoid colon, rectum(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 784

195

Autosomal recessive disorder presenting with explosive diarrhea with watery, frothy stools, and abdominal distention.

Congenital lactase (disaccharidase) deficiency(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 784

196

IBD presenting with thick wall appearance, transmural inflammation, skip lesions, knife-like ulcer, marked fibrosis and serositis

Crohn disease(TOPNOTCH)Robbins Basic Pathology, 9th ed., . 797

197

IBD which may presents with thin wall appearance, inflammation limited only to mucosa, marked pseudopolyps, broad-based ulcer, moderate lymphoid reaction, and toxic megacolon (complication)

Ulcerative colitis(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 797

198

Most important characteristic of colorectal adenomas that correlates with risk of malignancy.

Size of the tumor(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 808

199

An autosomal dominant disorder in which patients develop numerous colorectal adenomas as teenager caused by mutation of APC

Familial adenomatous polyposis(TOPNOTCH)Robbins Basic Pathology, 9th Ed p. 809

200

Most common syndromic form of colon cancer; colon cancers tend to occur at younger ages

HNPCC or Lynch syndrome(TOPNOTCH)Robbins Basic Pathoogy, 9th ed., p. 809

201

Most common location of HNPCC

Right colon(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 809

202

Autosomal dominant disorder characterized by familial clustering of cancers at several sites caused by DNA mismatch repair

HNPCC or Lynch syndrome(TOPNOTCH)Robbins Basic Pathoogy, 9th ed., p. 809

203

Location of colorectal cancer presenting with fatigue and weakness due to iron deficiency anemia

Right-sided colorectal carcinoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 623

204

Most common site of metastasis of colorectal adenocarcinoma

Liver(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 813

205

Which of the following statements regarding oral plaques is TRUE? (A) leukoplakia has a strong association with tobacco use (B) among the oral leukoplakias, those on the floor of the mouth have the highest rate of transformation to squamous cell carcinoma (C) hairy leukoplakia in AIDS patients have a high risk of malignant transformation (D) erythroplakia is less likely to undergo malignant transformation than leukoplakia

leukoplakia has a strong association with tobacco use (TOPNOTCH)Robbins Basic Pathology, 8th Ed pp 581-82

206

Which of the following is the most common site of oral cavity carcinoma? (A) lateral orders of the mobile tongue (B) floor of mouth (C) vermilion border of the lateral margins of the lower lip (D) hard palate

Vermillion border of the lateral margins of the lower lip(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 582

207

A 28 year old man presents with a 5 year history of a slow growing, painless, preauricular mass. FNAB showed clusters of bland cells admixed with myxoid material. He undergoes parotidectomy, and histopathologic examination of the mass shows bland epithelial cells forming clusters, ducts, and sheets, with surrounding myxoid stroma. There are also islands of cartilage. His tumor (A) can metastasize (B) is a chondrosarcoma (C) is the commonest tumor of the parotid gland (D) does not undergo malignant transformation

is the commonest tumor of the parotid gland (pleomorphic adenoma) (TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 584

208

A 55 year old male smoker undergoes parotidectomy for a cystic mass. Histopathology shows cystic spaces lined by abranching, two-tiered layer of epithelial cells, with well developed lymphoid tissue right beneath the lining. This tumor is thought to arise from (A) respiratory epithelium (B) heterotopic salivary tissue trapped within a lymph node (C) myoepithelial cells (D) macrophages

heterotopic salivary tissue in a lymph node (Warthin tumor) (TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 585.

209

A 60 year old chronic alcoholic man suddenly has massive hematemesis and dies. At autopsy, his lower esophagus shows bluish, dilated veins in the submucosa with surrounding erythema. One of the veins is ruptured. Which of the following is expected of his liver? (A) smaller than normal, firm, with nodular external surface (B) markedly enlarged, with multiple hemorrhages on cut section (C) smaller than normal, with a nutmeg appearance on cut section (D) markedly enlarged, with a greasy yellowish cut surface

smaller than normal, firm, with a nodular external surface (cirrhosis) (TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 587

210

A 24 year old female complains of heartburn, usually following spicy or sour meals. She takes antacids, with partial relief. She undergoes endoscopy where her lower esophagus appears diffusely erythematous with some epithelial erosions. A biopsy showed eosinophils in the epithelial layer, with basal zone hyperplasia. This is (A) reflux esophagitis (B) Barrett esophagus (C) esophageal candidiasis (D) squamous cell carcinoma

Reflux esophagitis(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 588