XVIII - The Male Genital System Flashcards Preview

Pathology TOPNOTCH > XVIII - The Male Genital System > Flashcards

Flashcards in XVIII - The Male Genital System Deck (111)
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1

An abnormal opening of the urethra along the ventral aspect of the penis.

Hypospadias(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 687

2

An abnormal opening of the urethra along the dorsal aspect of the penis.

Epispadias(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 687

3

A congenital malformation of the bladder associated with epispadias.

Bladder extrophy(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 688

4

A condition in which the prepuce cannot be retracted easily over the glans penis

Phimosis (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 688

5

Appears grossly as a solitary, plaquelike lesion on the shaft of the penis. Histologic examination reveals morphologically malignant cells throughout the epidermis with no invasion of the underlying stroma. Has potential for malignant transformation.

Bowen disease(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 688

6

Bowen disease which presents as an erythematous patch on the glans penis.

Erythroplasia of Queyrat(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 688

7

Occurs in young, sexually active males, histologically identical to Bowen disease. Presents with multiple reddish brown papules on the glans and is most often transient, with rare progression to carcinoma in immunocompetent patients.

Bowenoid papulosis (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 688

8

Appears as a gray, crusted, papular lesion, most commonly on the glans penis or prepuce, which infiltrates the underlying connective tissue to produce an indurated, ulcerated lesion with irregular margins.

Squamous cell carcinoma of the penis(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 689

9

A variant of squamous cell carcinoma characterized by a papillary architecture, less striking cytologic atypia, and rounded, pushing deep margins.

Verrucous carcinoma (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 689

10

Most common cause of scrotal enlargement, which is an accumulation of serous fluid within the tunica vaginalis usually secondary to infection or malignancy.

Hydrocele(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 689

11

Represents failure of testicular descent into the scrotum which involves the right testis more commonly than the left. Causes increased risk of sterility and development of testicular cancer.

Cryptorchidism(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 690

12

Most important cause of firm, painless enlargement of the testis.

Testicular neoplasms(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 690

13

Composed of sheets of large, uniform cells with distinct cell borders, clear, glycogen-rich cytoplasm, and round nuclei with conspicuous nucleoli. The cells are often arrayed in small lobules with intervening fibrous septa.

Seminomas(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 691

14

These tumors contain a mixture of medium-sized cells, large uninucleate or multinucleate tumor cells, and small cells with round nuclei that are reminiscent of secondary spermatocytes.

Spermatocytic seminoma(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 691

15

Ill-defined, invasive masses containing foci of hemorrhage and necrosis. Poorly differentiated, pleomorphic cells in cords, sheets, or papillary formation; most contain some yolk sac and choriocarcinoma cells

Embryonal carcinoma of the testis(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 692

16

Most common primary testicular neoplasm in children younger than 3 years of age.

Yolk sac tumors/endodermal sinus tumors(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 692

17

Low cuboidal to columnar epithelial cells forming microcysts, sheets, glands, and papillae, often associated with eosinophilic hyaline globules. (+) Schiller-Duval bodies

Yolk sac tumors/endodermal sinus tumors(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 692

18

Structures resembling primitive glomeruli, seen in yolk sac tumors.

Schiller-Duval bodies(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 692

19

Cytotrophoblast and syncytiotrophoblast without villus formation

Choriocarcinomas (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 692

20

Tissues from all three germ-cell layers with varying degrees of differentiation

Teratomas(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 692

21

Teratoma which contain fully differentiated tissues from one or more germ cell layers (e.g., neural tissue, cartilage, adipose tissue, bone, epithelium) in a haphazard array.

Mature teratomas (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 692

22

Teratoma which contain immature somatic elements reminiscent of those in developing fetal tissue.

Immature teratomas(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 692

23

Characterized by the presence of an acute, neutrophilic inflammatory infiltrate, congestion, and stromal edema of the prostate.

Acute prostatitis (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 695

24

Characterized by variable amount of lymphoid infiltrate, evidence of glandular injury, and, frequently, concomitant acute inflammatory changes of the prostate.

Chronic prostatitis (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 695

25

Nodular hyperplasia is usually more pronounced in what part/s of the prostate?

Inner (central and transitional) region of the prostate(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 696

26

Composed of proliferating prostatic glandular elements and fibromuscular stroma. The glandular lumina often contain inspissated, proteinaceous secretory material, termed corpora amylacea.

Nodular Hyperplasia of the Prostate (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 697

27

Major hormonal stimulus for proliferation in nodular hyperplasia of the prostate.

DHT (Dihydrotestosterone)(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 698

28

Most common area of the prostate affected by prostatic carcinoma.

Outer (peripheral) glands (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 698

29

Concentration of this biochemical marker is of great value in monitoring patients after treatment for prostate cancer.

Prostate specific antigen (PSA)(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 700

30

A commonly used method for grading prostatic carcinoma, which is based on features such as the degree of glandular differentiation, the architecture of the neoplastic glands, nuclear anaplasia, and mitotic activity.

Gleason system(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 700