XVIII - The Male Genital System Flashcards Preview

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Flashcards in XVIII - The Male Genital System Deck (111)
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A chronic venereal infection caused by the spirochete Treponema pallidum, whose fundamental microscopic lesion is a proliferative endarteritis and an accompanying inflammatory infiltrate rich in plasma cells.

Syphilis(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 702


An irregular, firm mass of necrotic tissue surrounded by resilient connective tissue. Contains a central zone of coagulation necrosis surrounded by a mixed inflammatory infiltrate composed of lymphocytes, plasma cells, epithelioid cells, giant cells, and a peripheral zone of dense fibrous tissue. Seen in tertiary syphilis.

Gumma(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 702


This stage of syphilis is characterized by the presence of an indurated chancre at the site of initial inoculation, associated with painless regional lymphadenopathy.

Primary Syphilis (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 702


Both nontreponemal and antitreponemal antibody tests are strongly positive in virtually all cases of this stage of syphilis.

Secondary syphilis(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 702


In males this is manifested most often as a purulent urethral discharge, associated with an edematous, congested urethral meatus. Gram stain of urethral discharge, demonstrates the characteristic gram-negative, intracellular diplococci.

Gonorrhea (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 705


A gram-negative intracellular bacterium that causes a disease that is clinically indistinguishable from gonorrhea in both men and in women.

Chlamydia trachomatis(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 707


C. trachomatis infection causing a triad of reactive arthritis, conjunctivitis and generalized mucocutaneous lesions.

Reiter syndrome(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 707


This STD is a chronic, ulcerative disease caused by certain strains of C. trachomatis, which presents with nonspecific urethritis, papular or ulcerative lesions involving the lower genitalia, regional adenopathy, or an anorectal syndrome.

Lymphogranuloma venereum (LGV) (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 707


This STD is an acute, ulcerative infection caused by Haemophilus ducreyi, a small, gram-negative coccobacillus. The lesion is an irregular ulcer, whose base is covered by a shaggy, yellow-gray exudate. Regional lymph nodes are enlarged and tender.

Chancroid (Soft Chancre) (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 707


A chronic inflammatory disease caused by Calymmatobacterium granulomatis. The organisms are demonstrable in Giemsa-stained smears of the exudate as minute coccobacilli within vacuoles in macrophages (Donovan bodies). Regional lymph nodes are typically spared.

Granuloma Inguinale (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 708


The initial lesions of this infection are painful, erythematous vesicles on the mucosa or skin of the lower genitalia and adjacent extra-genital sites. Cowdry type A inclusions appear as light purple, homogeneous intranuclear structures surrounded by a clear halo.

HSV 2(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 708


Caused by HPV types 6 and 11. Lesions vary from small, sessile lesions to large, papillary proliferations measuring several centimeters in diameter.

Condylomata acuminata (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 709


What is the most common cause of hydronephrosis in infants and children?

Ureteropelvic junction obstruction (TOPNOTCH)


Fiery red appearance of the cervix is associated with what type of infection?

Strawberry cervix is associated with T. vaginalis infection (TOPNOTCH)


Approximately 70% of prostate carcinoma will arise in what zone of the gland?

Peripheral zone ( posterior location) (TOPNOTCH)


Morphology: hallmark is nodularity due to glandular proliferation or dilation and to fibrous or muscular proliferation of the stroma



Morphology: appear as minute, disseminated abscesses or diffuse edema, congestion, and boggy suppuration of the entire prostate

Acute prostatitis (TOPNOTCH)


Morphology: aggregation of numerous lymphocytes, plasma cells, and macrophages as well as neutrophils within the prostatic substance

Chronic prostatitis (TOPNOTCH)


Morphology: tumor cells are arranged in distinctive trabeculae with a tendency to form cordlike structures resembling immature seminiferous tubules

Sertoli Cell Tumors or Androblastoma (TOPNOTCH)


Morphology: rod shaped crystalloids of Reinke

Leydig/Interstitial Cell Tumors (TOPNOTCH)


What is the most common form of testicular neoplasm in men over the age of 60?

Testicular Lymphoma (TOPNOTCH)


Morphology: disorganized collection of lands, cartilage, smooth muscle, and immature stroma

Teratoma of the testes (TOPNOTCH)


What do you call the structures resembling endodermal sinuses that may be seen in Yolk Sac Tumor?

Schiller Duval Bodies (TOPNOTCH)


Morphology: reveals large cells with distinct cell borders, pale nuclei, clear or watery appearing cytoplasm, prominent nucleoli, and a sparse lymphocytic infiltrate

Seminona (TOPNOTCH)


Within how many hours should the testes be explored surgically and untwisted manually so the testes will be viable after a testicular torsion?

Within 6 hours(TOPNOTCH)


Morphology: clear vacuolization of the prickle cells

Condylomata acuminatum (koilocytosis) (TOPNOTCH)


What HPV DNA type is found in approximately 80% of Bowen Disease and bowenoid papulosis?



What type of bladder cancer is associated with long standing schistosomiasis?

Squamous cell carcinoma (TOPNOTCH)


In bladder carcinoma, the major decrease in survival is associated with tumor invading what layer of the bladder?

Muscularis propria (detrussor muscle) (TOPNOTCH)


Umbrella cells with abundant cytoplasm, cells with oval nuclei often with nuclear grooves can be seen in what type of epithelium?

Urothelium(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 959