Year 3

Question 1

What STI does not stain with gram stain and is spiral shaped?

Answer 1

Treponema pallidum

Question 2

What part of the bone is the bone marrow found in?

Answer 2

Medullary cavity

Question 3

Woman with six months of secondary ammenohhrae and a negative pregnancy test

they had chemotherapy for renal cancer when they were litttle

Answer 3

Premature Ovarian failure

Radiotherapy or Chemotherapy is a risk factor

Question 4

How can premature ovarian failure be confirmed?

Answer 4

High FSH

Question 5

What endocrine thing to people with severe depression get?

Answer 5

Adrenal enlagement

increased cortisol

Increased ADCTH

Dexamethasone suppresion test doesnt work (cortisol non-supression)

Question 6

An insult to what area of the brain would cause:

Receptive aphasia

Expressive aphasia

Nominal aphasia

Answer 6

Receptive - Wernicke’s area

Expressive - Brocca’s area

Nominal aphasia - Angular Gyrus

Question 7

During which stage of embryogenesis are the germ layers formed?

Answer 7

Gastrulation

Question 8

What is the most common reason for a lady to have X-linked haemophilia with the phenotype expressed?

Answer 8

Normal X inactivation

The other X chromosome must not be expressing the gene

Question 9

What kind of dementia gives you hallucinations the most?

Answer 9

Lewy body

Question 10

In myasthenia gravis what do the antibodies attack?

Answer 10

Postsynaptic acetylcholine receptors

Question 11

What enzyme transcribes genetic material

Answer 11

RNA polymerase

Transcribes messanger RNA to DNA

Question 12

what does HELLP stand for?

Answer 12

Found in Pre-Eclampsia

Haemolysis

Elevated

Liver enzymes

Low

Platelets

Question 13

What blood tests are usefull in suspeced HELLP syndrome?

Answer 13

FBC

U&E

LFT

Question 14

What is Tetracycline?

Answer 14

Antibiotic

NOT TO BE USED IN KIDS UNLESS THEY WANT YELLOW TEETH

Question 15

What cells are usally raised in each of the scenarios?

allergy

Bacteria

Virus

Answer 15

Eosinophils

Neutrophils

Lymphocytes

Question 16

What is the nerve root for the biceps reflex?

Answer 16

C5/6

(you only have biceps in s5 and s6)

Question 17

What nerve root is responsible for the ankle reflex?

Answer 17

S1

only 1 injury basketball players get

Question 18

What nerve roots is responsible for the knee reflex?

Answer 18

L3/4

right fist 1

left fist 2

right knee 3

left knee 4

Question 19

Which hormone during pregancny causes enlargement of the breast and mammary gland for lactation?

Answer 19

Prolactin

Question 20

How do you treat partial seizures without loss of consciousness?

Answer 20

Carbamazepine

Question 21

How do you treat neuroeplieptic malignant syndrome?

Answer 21

Bromocriptine

Question 22

At whih developmetal stage does the embryo implant into the uterus ?

Answer 22

blastocyst

Question 23

What moves the oxygen dissosiation curve to the right?

Answer 23

Increased H+

Increased CO2

Increased 2,3DPG

Increased Temp

Question 24

How do you treat endometriosis?

Answer 24

Combined oral contraceptive pill

Question 25

What drug reduces the effectiveness of the combined oral contraceptive pill?

Answer 25

Phenytoin

Question 26

What is Phenytoin used for?

Answer 26

tonic clonic seizures

Question 27

What is a mobile smooth breast lump?

Answer 27

Fibroadenoma

Question 28

What so memantine and how does it work?

Answer 28

Alzheimers medication Blocks NMDA-type glutamate receptos

Question 29

What is the first investiagion you do when investigation heavy menstural bleeding?

Answer 29

FBC for anaemia

Question 30

What drug is best for a young lady of has had two tonic clonic seizures 2 months apart?

Answer 30

Lamotrigine as it is the least teatrogenic

Question 31

What is wilsons disease and how is it acquired?

Answer 31

Autosomal recessive condition Copper accumulation Kayser-Fleischer rings

Question 32

How is Becker's muscular Dystrophy inherrited?

Answer 32

X linked recessive

Question 33

What is myoclonic epilepsy with ragged red fibres?

Answer 33

Mitochondrial disease where clumps of mitochondria accumulate in the muscle fibres giving a reaged red appearance

Question 34

What neurotrasmitter is lacking in Sedative drug use withdrawl?

Answer 34

GABA

Question 35

What neurotransmitter is low in depresion?

Answer 35

5-Hydroxytryptamine

Question 36

what is 5-hydroxytryptamine?

Answer 36

Serotonin

Question 37

What nerve supply causes contraction of the destruser muscle?

Answer 37

parasympathetic ( you are relaxed when you pee)

Question 38

At what bladder volume will you have the desire to pee?

Answer 38

Around 250mls

Question 39

What is Lamotrigine and how does it work?

Answer 39

Epliletic drug Blockage of volatage sensitive sodium channels

Question 40

What what haemogloin level would you consider a blood transfusion?

Answer 40

8 g/l or less

Question 41

What drug inhibits the action of acetylcholinesterase?

Answer 41

Galantamine

Question 42

what is galantamine used for?

Answer 42

Dementia

Question 43

what is gram negative diplococci in urethral pus from a male patient?

Answer 43

Gonococcal infection

Question 44

What is the presense of clue cells a clue for ?

Answer 44

Bacterial vaginposis

Question 45

What sign suggests conenital cardiovascular disease in a newborn infant?

Answer 45

Delay in fermoral pulses

Question 46

What organisim produces both elementary and reticulate bodies ?

Answer 46

Chlamydia trachomatis

Question 47

What hormone is measured to asses ovarian reserve prior to IVF?

Answer 47

Anti-mullerian hormone

Question 48

What artery is most likely to cause bleeding after insertion of a lateral abdominal port during female laparoscopic sterilisation?

Answer 48

inferior epigastric artery

Question 49

What artery is likely to be injuried during incision of a barthrolin's abscess?

Answer 49

Internal pudendal artery supplies the labia and clitoris

Question 50

What is trichomonas vaginalis?

Answer 50

Single cell protozoal parasite

Question 51

What nerve root is responsible for knee flexion?

Answer 51

L4

Question 52

What supplements should a pregant lady of 8 weeks ttake?

Answer 52

Vitamin D too late for folic acid as the neural tube has closed

Question 53

A SPECT scan shows patchy reduced attenuation throughout the brain?

Answer 53

Vascular dementia

Question 54

What is aplastic aneamia?

Answer 54

Bone marrow failure

Question 55

What investigation should be done before starting lithium carbonate?

Answer 55

U&E (it can impair renal function)

Question 56

What is the most common inheritance of spherocytosis?

Answer 56

Autosomal Dominant

Question 57

Which area of the brain is affected first in Alzheimer's disease?

Answer 57

Nucleus Basalis of Meynert