Year 5 passmed Flashcards

(62 cards)

1
Q

abx of choice to treat mycoplasma

A

doxy or azithromycin

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2
Q

side effects of doxycycline

A

photosensitivity
discoluration of thyroid gland
fontanelle bulging in infants
tooth discoluration
GI discomfort

dont give them in pregnancy

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3
Q

What is the most appropriate test to check for latent tuberculosis?

A

A TB skin test (“Mantoux”) can show if you have latent TB infection.

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4
Q

exmape of a non-lactose fermenting, oxidase-positive, gram-negative bacilli

A

pseudomonas aeruginosa

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5
Q

oxidase negative bacteria common

A

Oxidase (-) Burkholderia spp.
E. coli.
Proteus spp. Salmonella spp. Shigella spp.

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6
Q

oxidase positive bacteria

A

Oxidase (+) P. aeruginosa. Aeromonas spp.

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7
Q

hepatomegaly causes

A

infections: Hep A, B or C , cytomegalovrius and mononucleosis

Alcohol

autoimmune - sarcoidosis and SLE

Genetic - hemochromatosis, wilsons disease, alpha 1 anti-typrsin

cogestive heart failure and thrombosis

neopalstic; leuakemia, lymphoma , HPC

sicle cell anaemai

pregnancy

amyloidosis

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8
Q

generalised liver disease sx

A

abdominal pain
bruising
fatigeu
itching
jaundice
muscle aches
nausea
poor appetite
swelling

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9
Q

splenomegaly causes

A

malaria
hodgkins
leukaemia
HF
cirrrhosis
tumours
viral bacterial and parastie
SLE and RA
mononcuelosis
suphylis

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10
Q

headache, myalgia, fever and a cough. On auscultation her chest is clear but she has a temperature of 38.6ºC - these are all typical flu sx what causes the flu

A

influenza

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11
Q

cause of the common cold

A

rhinovirus

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12
Q

what genital ulcers are painful and whats more common than the other

A

painful: herpes much more common than chancroid

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13
Q

what genital ulcers are painless and whats more common

A

painless: syphilis more common than lymphogranuloma venereum

behecets also cause ulcers - do not know if painful or not

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14
Q

chancroid caused by

A

Chancroid is a tropical disease caused by Haemophilus ducreyi. It causes painful genital ulcers associated with unilateral, painful inguinal lymph node enlargement. The ulcers typically have a sharply defined, ragged, undermined border.

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15
Q

lymes disease abx tx

A

doxycycline
amox if preg

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16
Q

management of pt with bacterial meningitis (4)

A

IV access to get bloods and cuture
IV abx - cefotaxime if 3m-50 and over 50 cefotaxime and amox
Iv dexamethaone - particularly if pneumococcal - improve outcomes by reducing neurological sx
CT scan

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17
Q

when getting an LP what are you looking and testing for

A

glucose, protein, microscopy and culture
lactate
meningococcal and pneumococcal PCR
enteroviral, herpes simplex and varicella-zoster PCR
consider investigations for TB meningitis

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18
Q

what do you give to contacts of meningitis if close contact witin 7 days

A

oral ciprofloxacin or rifampicin

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19
Q

if you have chronic hepatitis what vaaccine should you be offered

A

one-off pneumoccoal vaccine

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20
Q

choice of abx in cellultiis in preg

A

erythromcyin - if not preg clairthomycin

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21
Q

most common cause of viral meningitis

A

Coxsackievirus or other enteroviruses

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22
Q

characterised by a prodrome, abdominal pain and bloody diarrhoea what infection for gi infection

A

campylobacter

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23
Q

bacterial vag tx
can in preg and breastfeed

A

Metronidazole 400mg bd for 5 days

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24
Q

Patient has had a full course of tetanus vaccines, with the last dose < 10 years ago do you need any tetanus tx

A

no vaccine nor tetanus immunoglobulin is required, regardless of the wound severity

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25
Patient has had a full course of tetanus vaccines, with the last dose > 10 years ago do you need vaccine
yes but depends if tetanus prone wound- puncture , foregin body burn , bite : reinforcing dose of vaccine high-risk wounds- heavy contamination (e.g. compound fractures, delayed surgical intervention, significant degree of devitalised tissue): reinforcing dose of vaccine + tetanus immunoglobulin
26
pneumonia pathogen in alcoholics
klebsiella
27
worsening cellulitis with worsening pain in keeping with physical features what you thinking and who should you refer to
nec fasc and surgeons
28
Chest X-ray shows a partially-filled cavity with a crescent of air post TB
aspergilloma
29
what is metronidazoles affect on warfarin
Metronidazole increases the anticoagulant effect of warfarin increasing INR as delayed antucoagualtn effect
30
most likely pathogen associated with gangrene
Clostridium perfringens is the most likely pathogen to be associated with gangrene.
31
cavitating lesion causing pneumonia what pathogen
staph aureus
32
Fever, abdominal pain, constipation, 'rose' spots
typhoid - salmonella typhi
33
oral herpes what cause
HSV-1 is more commonly associated with oral herpes
34
despite taking penicillin abx - Which organism is he particularly susceptible to, despite taking prophylactic antibiotics?
h.influenzae
35
if HIV is dx when should antiviral therapy be started
Antiretroviral therapy should generally be started as soon as HIV is diagnosed Prescribe two nucleoside reverse transcriptase inhibitors (NRTI) and a protease inhibitor (PI)
36
one solitary gential keratinised wart - how do you treat
solitary, keratinised warts: cryotherapy
37
if you have multiple non- keratinised warts how do you treat
multiple, non-keratinised warts: topical podophyllum
38
what is lemierre syndrome
Lemierre's syndrome presents with thrombophlebitis of the internal jugular vein following an anaerobic oropharngeal infection.
39
if abx treatment is needed for a campylobacter infection what should you give
Campylobacter infection is often self-limiting but if severe then treatment with clarithromycin may be indicated
40
The BNF recommends treating invasive diarrhoea (causing bloody diarrhoea and fever) with
ciprofloxacin Most viral or bacterial gastroenteritis do not require treatment. The BNF recommends antibiotics for bacterial gastroenteritis in severe infections or in immunocompromised patients. Clarithromycin is used for traveller's diarrhoea and non-invasive diarrhoeal illnesses when treatment is necessary.
41
Erratic blood glucose control, bloating and vomiting think
gastroparesis
42
kocher criteria for septic arthritis
Fever: A temperature of 101.3°F (38.5°C) or higher Erythrocyte sedimentation rate (ESR): An ESR of more than 40 millimeters per hour (mm/hour) White blood cell (WBC) count: A WBC count of more than 12,000 cells/mm3 Inability to bear weight: The patient is unable to put weight on the affected si modified adds on crp will also have restricted movement needing synvoial fluid sampling, joint imgiign and blood cultures
43
difference between bacterial and viral csf
bacterial low glucose and high protein vial high glucose and normal protein fungal low glcuose and high protein
44
cardiac tamponade follows what
truma, MI, TB or inf , lupus, cancer , CKD, surgery
45
risk factors for GI bleed
NSAID, anticagoaulans, SSRI alcohol and smoke colitis or ulcers surger cancer RF , liver dissease vomit radiation tx can increase risk of peptic ulcers
46
how does constrictive pericarditis lead to heart failure
pericardium thickens and stiffens making it difficult for the heart to expand. This prevents the heart chambers from filling with enough blood, which can to lead to heart failure sx such as swelling peipherally taifgue and SOB
47
Gonorrhoea 1st and 2nd line
Im ceft then oral cefixime 400mg (single dose) + oral azithromycin 2g (single dose)
48
extnsive OE
Flucloxacillin
49
pelvic inflammatory disease tx 3 drugs
Doxycycline + metronidazole + ceftriaxone
50
A test of cure MSU should be sent in pregnant women treated for a UTI what is it post abx
Midstream urine microscopy and culture
51
meningitis over 50 what tx
IV cefotaxime and amoxicillin
52
Genital wart treatment if solitary or multiple
multiple, non-keratinised warts: topical podophyllum solitary, keratinised warts: cryotherapy
53
chlam in preg what to treat
azithromycin
54
HIV what vaccines are contraindicated live vaccines
Yellow fever Oral polio Intranasal influenza Varicella Measles, mumps and rubella (MMR) TB BCG
55
Campylobacter infection is often self-limiting but if severe then treatment with
clarithromycin
56
For a patient undergoing an elective splenectomy, when is the optimal time to give the pneumococcal vaccine?
two weeks before surgery
57
when do you treat toxoplasmosis
only if immunosuppressed pts
58
Which of the following combinations of vaccinations are routinely offered to pregnant women in the UK?
Influenza and pertussis
59
ALL tb pt what else should be offered
HIV test
60
in sarcoid why do you need CXR
a mass of granulation tissue, typically produced in response to infection, inflammation, or the presence of a foreign substance. non casating ( tissue turning into soft cheese like substance) granulomas
61
Raised ALP in the presence of normal LFT's should raise suspicion
malignancy
62
Heparin can cause hyperkalaemia
true