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1: dna and chromosome structure, function and gene discovery

This class was created by Brainscape user Thomas Monk. Visit their profile to learn more about the creator.

By: Thomas Monk
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Decks in this class (15)

1. DNA structure, packaging, histone modification and chromatin
What are the 3 components of dna,
Describe the bonding in dna,
Describe the wider structure of dna
6  cards
2. Chromosome structure and organisation in humans
Describe the structure of a chrom...,
What are the 3 types of chromosome,
What is the centromere formed of ...
10  cards
4. Gene structure
What are the two main types of re...,
What is a gene promoter what are ...,
What is an enhancer element
6  cards
5. DNA replication
Where does dna replication initiate,
What enzymes are involved in the ...,
What type of dna polymerase repli...
10  cards
6. Cell cycle, mitosis, meiosis and recombination
What are the main stages of inter...,
What are the main stages of mitosis,
What is the first checkpoint in t...
6  cards
7. Transcription, mRNA processing (excluding splicing) and translation
What happens in transcription,
How is transcription inititated,
Name 3 promoter elements
7  cards
8. Splicing
What is the purpose of splicing,
How are introns defined,
Where is the branch site what doe...
9  cards
9. Nonsense mediated decay
What is the purpose of nmd,
How does nmd protect the cell,
What is non stop mediated decay
4  cards
13. Mechanisms of mutation in DNA & 16. Origins of other structural abnormalities
What are the 3 main mechanisms of...,
What is ber what s its role how d...,
Give an example of a gene involve...
25  cards
14. Pseudogenes and clinical relevance
What is a pseudogene,
What are the two main classes of ...,
How do non processed pseudogenes ...
8  cards
18. LCRs and the origin of genomic disorders
What are lcrs,
What type of variation to lcrs le...,
What mechanisms cause non recurre...
10  cards
21. X-inactivation in females
What is x in activation what is t...,
When does x inactivation occur,
Describe the structure of the ina...
11  cards
19. Mosaicism - origins & clinical significance
Define mosiacism,
What is chimerism,
What factors influence the phenot...
7  cards
20. Epigenetics / DNA methylation across the genome
What is meant by the term epigene...,
What is the role of dna methylation,
Describe the process of dna methy...
11  cards
22. Origin of UPD - mechanisms and detection methods
What is upd,
Who can upd cause disease,
Why can upd cause miscarriage
19  cards

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1: dna and chromosome structure, function and gene discovery

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