04.02 Renal Dosing Flashcards Preview

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Flashcards in 04.02 Renal Dosing Deck (14):
1

CrCl _____estimates GFR

over

2

Acute renal failure: SCr obtained before steady state will ______estimate the SCr and ______estimate CrCl and GFR

Acute renal failure: SCr obtained before steady state will UNDERestimate the SCr and OVERestimate CrCl and GFR

3

Which method is good for Moderate/High GFR?

CKD-EPI

4

Methods that adjust for race

MDRD and CKD-EPI

5

Methods that predict CrCl

Cockcroft-Gault

6

Methods that predict GFR

MDRD and CKD-Epi

7

Good for low GFR

MDRD

8

Best for ELDERLY

CKD-EPI marginally better than MDRD at GFR >60, both are better than CG

9

CG _____estimates renal function and ______doses older patients

CG UNDERestimates renal function and UNDERdoses older patients

10

Obesity

CG-ABW preferred (also CG-LBW or MDRD corrected for BSA)
Only use estimation as a starting point - due to the large variability in the estimation should measure GFR or CrCl

11

IBW as a substitute for LBW _____estimates CrCl as obese patients have _____total lean body mass than normal weight pts

IBW as a substitute for LBW UNDERstimates CrCl as obese patients have GREATER total lean body mass than normal weight pts

12

For patients with advanced age (>80yo), low body weight and modestly elevated SCr the _____method is superior

Cockcroft-Gault

13

Critically ill ICU pts

Both CG and MDRD overestimate GFR - unsuitable
Obtain a 12-24 h CrCl measurement

14

Children 1-16 years old

Schwartz equation:

0.413 x height (cm)/SCr