067 Autoimmunity and Neurological Disorders Flashcards
1
Q
What do VLA-4 on WBCs bind to on blood epithelium during recruitment?
A
VCAM-1
2
Q
What does the receptor P-selectin on surface of blood vessel bind to?
A
PSGL-1 on white blood cells
3
Q
What T cell is essential in pathogenesis of inflammatory disease?
A
Th17 that recruits IL17 and IL22
4
Q
What is the main URT cause of gullain barre syndrome?
A
Campylobactor jejuni –> GMC liposaccharide which is very similar to ganglioside GMI on nerve cell membranes
5
Q
How do you treat Guillain Barre syndrome?
A
Plasma exchange or IgG exchange
