#1 Flashcards
(34 cards)
Identify the components of the different Nucleic Acids.
Nitrogen base
5 carbon sugar
Phosphate
Draw the chemical structure for Deoxyribonucleic Acid nucleotide.
On notes
Identify the 3’ Carbon and the 5’ Carbon on the DNA nucleotide.
On nktes
Locate the PO43- and the OH- molecules on the nucleotide.
On notes
Identify the location of the Nitrogen Base on the nucleotide.
On nktes
Draw and explain the difference in chemical structure between RNA and DNA.
RNA has OH & OH
DNA has H & OH
Locate Telomeres on a human chromosome.
Ends of the chromosomes
Specify the base pairs present in telomeres, and their specific pattern.
5’-T-T-A-G-G-G-3’
3’-A-A-T-C-C-C-5’
Chromosomes can have how many telomeres and bp
2500 telomeres & 15000 bp
Some telomeres are lost when
On the lagging strand during replication
How many telomeres & bp are lost during replication
30-200 bp
5-30 telomeres
Once a cell loses enough telomeres,
It can’t divide anymore
-about 50 divisions
Explain the function of Telomerase and how it is related to aging and tumor proliferation.
Telomerase forms new telomeres & copies in the reverse direction (3’-5’)
Adult cells don’t have what
Active telomerase
Cancer cells reactivate what
Telomerase
Explain the significance of the Genetic Code; what it is, where it is located, what it does, and
how it contributes to life.
The genetic code is the order of the nitrogen base pairs in DNA
If you change the order of the nitrogen bases & you change the characteristics of an organism
DNA is laid down in the
5’ to 3’ direction
The leading strand goes
3’ to 5’
The lagging strand goes
5’ to 3’
The lagging strands form what
Okazaki fragements
DNA replication
Making more DNA
Leading strand starts where
At the origin & moves towards 5’
Lagging strand starts at
Replication fork & moves towards origin
Dna helicase
Unzips and untwisted DNA for replication
