1. GI Part 1 Flashcards

1
Q

List the functions of the GI system (5)

A
  1. transportation of food
  2. digestion of food in absorbable particles
  3. regulation of water and electrolyte balance
  4. immunologic barrier (GALT)
  5. thermoregulation – fluid intake, panting
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2
Q

general differences between different GI systems

carnivores
ruminants
horses
birds

A

carnivorous - big stomach, relatively short intestinal tract

ruminants - fermentation in forestomach system

horses - fermentation in the large intestine (hindgut)

birds - food storage in the crop, glandular stomach called proventriculus, muscular stomach called gizzard

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3
Q

species differences in prehension

horses
cattle
goats/sheep
pigs
carnivores
A

horse - lips (eating from manger), incisors (grazing)

cattle - tongue (wrap around forage), incisors

goats/sheep - tongue, lips

pigs - snout, mandible

carnivores - canines, incisors, forelimbs

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4
Q

define mastication

A

first act of digestion

involves actions of teeth, jaws, and tongue

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5
Q

describe carnivorous mastication

A

very sparsely, movement of mandible is vertical

molars and premolars in the upper and lower jaws move against each other like scissor blades

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6
Q

describe herbivorous mastication

A

spend long time masticating

upper and lower jaws are large providing room for teeth with large chewing surfaces

movements are horizontal

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7
Q

functions of GI tract movements (4)

A
  1. propel ingesta from one location to the next
  2. retain ingesta at a given site for digestion, absorption, or storage
  3. break food material physically and mix it with digestive secretions
  4. circulate ingesta so all portion come in contact with absorptive surfaces
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8
Q

what are the 2 phases of deglutition

A
Voluntary phase (oral phase)
food is in the oral cavity and is molded into a bolus; using the tongue it will be pushed back into the pharynx 

when the food enters the pharynx –> activation of sensory nerve endings –> initiation of involuntary phase

Involuntary phase (swallow reflex)
occurs within the pharynx and esophagus --> directs food into digestive system (away from upper airways)
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9
Q

sequence of events of deglutition (4)

A
  1. soft palate elevated closing the pharyngeal opening of the nasopharynx preventing food from entering the internal openings of the nostrils
  2. tongue is pressed against the hard palate closing off the oral opening
  3. epiglottis is moved backwards covering the entrance of the trachea preventing the movement of food into the respiratory system
  4. upper esophageal sphincter opens and food transported through esophagus by peristaltic contractions; the entrance of the trachea is reopened and respiration continues
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10
Q

disorders of deglutition

A

Dysphagia - difficulty in swallowing due to neuromuscular disorder of mechanical obstruction

Oropharyngeal Dysphagia - malfunction of the pharynx and upper esophageal sphincter

Esophageal Dysphagia - malfunction of the esophagus

Aspiration - a dysphagia in which food particles/fluids or stomach contents (acid reflux) reach the upper airways

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11
Q

what is the regulatory center for energy homeostasis

A

hypothalamus

hunger center - Nucl. paraventricularis, lateral hypothalamus fields, perifornical region

satiety center - Nucl. ventromedialis

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12
Q

regulation of food intake - neuropeptides in the hypothalamus

A

stimulatory - neuropeptide Y (NPY), orexin

inhibitory - melanocyte stimulating hormone (MSH)

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13
Q

what does MSH do

A

inhibits hunger and increases energy consumption

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14
Q

regulation of food intake - non hypothalamic hormones

A

stimulatory - ghrelin

inhibitory - cholecystokinin (CCK), peptide YY (PYY), leptin, insulin

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15
Q

where is CCK produced and what does CCK do

A

produced by small intestine

inhibits food ingestion

released after a meal while food being digested in small intestine

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16
Q

what does the Y stand for in PYY

A

Y = tyrosine

PYY has 2 tyrosines

17
Q

what does leptin do

A

fat cells –> inhibits NPY release and activates MSH release and activity

18
Q

where is insulin released and what does it measure/indicate

when is it released

A

pancreas –> glucose availability

released after food absorbed and glucose reaches blood –> tells us to stop eating because we have enough sugar

19
Q

where are non hypothalamic hormones produced

A

GI tract

20
Q

what are the 3 major salivary glands and what type of secretions does each do

A

parotid gland – serous secretion

mandibular gland – seromucous secretion

sublingual gland – seromucous secretion

21
Q

what are some smaller salivary glands

A

ventral jaw glands
palate, pharyngeal glands
lips glands (labiales)
zygomatic glands

22
Q

what are the primary functions of saliva (4)

A
  1. protection of the buccal mucosa and teeth
  2. facilitation of deglutition
  3. initiation of enzymatic carbohydrate digestion (humans and pigs –> amylase)
    amylase - starts digestion of carbohydrates (starch)
  4. pH regulation (bicarbonate)
23
Q

secondary functions of saliva (3)

A
  1. immunologic function – Igs (IgA)
  2. thermoregulation – panting in dogs
  3. defense mechanism in some species – spitting (llamas and alpacas)
24
Q

what does salvia consist of

A

water and electrolytes (Na, K, Cl, HCO3)

25
Q

where is primary saliva formed and what is it made of

A

produced in the acinus (glandular epithelium)

contains Cl, Na, H2O

26
Q

where is secondary saliva produced and what is it made of

A

produced in ducts

contains K, HCO3

in the salivary gland ducts, some Cl is resorbed and HCO3 is released; some Na is resorbed and K is released

27
Q

regulation of saliva secretion - parasympathetic

A

parasympathetic system – N. facialis, glossopharyngeus

M3 receptors

Contraction of myoepithelial cells
Increased secretion (saliva more dilute)
28
Q

regulation of saliva secretion - sympathetic

A

sympathetic system – 3 first thoracal segments

a-1 receptors

Stimulation of acinar cells that produce mucin

Secretion of small volumes of consistent (mucus) saliva

Small amount of concentrated saliva

29
Q

stimulation of saliva secretions

A

Innate (reflex) - through contact with buccal mucosa (mechanoreceptors)

Conditioned - through sight, smell, or imagination of food