10/11 - CVA Pathology and Medical Management Flashcards

(55 cards)

1
Q

More common side for CVA

A

Left (possibly due to fluid dynamics of L vs R branch from aortic arch); MCA most common

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2
Q

Transient Ischemic Attack (TIA)

A

Transient episode of neurological dysfunction

Temporary disturbance in blood supply to the brain spinal cord or retina without permanent death of tissue.

Symptoms usually last ? 1 hour.

3-17% 90-day risk of a completed stroke.
Up to 50% occur within 48 hours of the TIA

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3
Q

Stroke

A

Disruption of the vascular supply to the brain brainstem or spinal cord that leads to infarction (death) of CNS tissue.

Symptomatic or silent.
Symptomatic strokes manifest by cerebral or spinal dysfunction caused by CNS infarction.
Silent strokes are documented CNS infarction that was asymptomatic

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4
Q

Stroke epidemiology

A

?795 000 strokes per year in the United States
?610 000 are first strokes
> 5 000 000 stroke survivors in the US
#1 cause of disability in the US
4th leading cause of death in the US (#2 worldwide)

4-8% recurrence in 1st 3 months

Overall 7-10% recurrence/year
Highest in first year

Survival*
~50% at 3 years
~33% at 10 years
*comorbidities common

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5
Q

Ischemic stroke

A

61-87%; Thrombotic Vs Embolic; Large Vs Small vessel; Arterial Vs Venous

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6
Q

Hemorrhagic

A

Intraparenchymal Vs Subarachnoid
Primary Vs Secondary (conversion)
Higher proportion of hemorrhage in children

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7
Q

Large vessel thrombotic stroke

A

Slow stuttering onset due to gradual occlusion +/- collateral circulation
Possibly preceded by TIA

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8
Q

Small vessel thrombotic ?lacunar? stroke

A

Associated with longstanding hypertension and diabetes

Basal ganglia internal capsule and brainstem

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9
Q

Cardioembolic Etiologies in Ischemic Stroke

A
Valvular atrial fibrillation 
Nonvalvular atrial fibrillation 
Acute myocardial infarction 
Bacterial endocarditis
DVT with a patent foramen ovale
Mitral valve prolapse
Prosthetic mechanical heart valves
Possible injury in multiple vascular distributions
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10
Q

Cerebral venous thrombosis

A

Relatively rare

Higher risk in peripartum period OCPs + smoking coagulopathies

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11
Q

Hemorrhagic Stroke facts

A
Intraparenchymal (75%) vs. subarachnoid (25%)
Fast  large volumes of blood
Increased mortality
If survived  decreased morbidity
BP and ICP control
MAP = 1/3 (SBP-DBP) + DBP
MAP-ICP=CPP
Vomiting  systolic BP >220 mm HG  severe headache  coma  decreased level of consciousness and progression over minutes-hours suggest hemorrhage.

Rapid deterioration in neurological status is common

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12
Q

Intraparenchymal Hemorrhagic Stroke

A

75% of hemorrhagic strokes

Hypertensive hemorrhages
Rupture of micro-aneurysms
Putamen»thalamus pons cerebellum and cerebral hemispheres.

Non-hypertensive hemorrhages
Sympathomimetic agents
Cavernous angiomas amyloid angiopathy intracranial tumors bleeding disorders trauma vasculitis hemorrhagic conversion infection

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13
Q

Subarachnoid Hemorrhagic Stroke

A
25% of hemorrhagic strokes
Progressive deficits over minutes to hours 
Headache and decreasing consciousness
Etiologies:
Saccular aneurysms
Most common cause of SAH
45 % risk of death in the 1st 30 days
Most within a few days
Arteriovenous malformations (AVMs)
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14
Q

EMS Management of stroke

A
Airway  breathing and circulation (ABC)
Cardiac monitoring 
Intravenous access 
Oxygen  if needed
Rapid identification of stroke/time of onset
Rule out (and treat) stroke mimics
Keep NPO (no food or drink)
Alert receiving ED 
Rapid transport to closest appropriate facility
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15
Q

ED Evaluation

A
General medical examination
Identify contributing factors:
Drug exposures  trauma  cardiac conditions
NIH Stroke Scale
Glasgow Coma Scale
Dysphagia screen
Airway  breathing and circulation (ABC)
Adequate hydration
Treat elevated temperatures
Glucose control
Cardiac monitoring for 1st 24 hours
Cautious initial approach to HTN
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16
Q

Non-enhanced brain CT scan (NECT) (Medical Diagnosis)

A

The acute study of choice
Quick and affordable
Blood and bone visible
Radiation exposure
Does not show brain tissue changes such as hypoxia/anoxia
Helps identify nonvascular etiologies
E.g. brain tumor
Certain findings may predict hemorrhage with TPA
Early infarct signs including edema and mass effect
Poor visualization of small cortical and subcortical acute infarcts
Not as useful for imaging the ?posterior fossa? because of bone artifacts

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17
Q

Vascular Evaluation

A
Conventional angiogram
Still appears to be gold standard
Magnetic Resonance Angiogram (MRA)
CT angiogram
Carotid ultrasound 
Transcranial doppler ultrasound
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18
Q

Magnetic Resonance Imaging

A
Better than CT
Identifies:
Acute small cortical strokes
Posterior fossa lesions
Acute vs. chronic lesions 
Subclinical satellite lesions
May be preferable when TPA is not considered
No radiation exposure
Considerations:
More time consuming and less available
Patient contraindications
Claustrophobia
Internal devices
Metal implants
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19
Q

AHA/ASA Guidelines for Ischemic Stroke - Medical Treatment

A
Airway  breathing and circulation (ABC)
Airway protection in dysphagia or decreased LOC/NPO
Adequate hydration
Treat elevated temperatures
Glucose control
Cardiac monitoring for 1st 24 hours
Cautious initial approach to HTN
Oxygen only if hypoxic
Identify etiology of hypovolemia or hypotension
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20
Q

AHA/ASA Guidelines for Ischemic Stroke - Medical Treatment

A

Intravenous (IV) TPA given in ? 3 hours of stroke onset in appropriate patients
Possible expansion of window to 4.5 hours in selected patients
SBP <120
PT implications?

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21
Q

AHA/ASA Guidelines for Hemorrhagic Stroke ? Medical Treatment

A
ABCs 
Rapid transport
Immediate imaging
Careful blood pressure management 
Normalize fluid balance and electrolytes
Control seizures
Normalize body temperature
Correct any bleeding disorders (specific to the problem)
DVT prophylaxis
Clot evacuation and ventricular drainage as required
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22
Q

Pressure Monitors

A

Control intracranial pressure (ICP)
Elevate head osmotherapy (mannitol) hyperventilation barbiturate coma sedatives ventricular monitors lasix
Risk of decreasing cerebral perfusion pressure
Cerebral perfusion pressure = mean arterial pressure ? intracerebral pressure (CPP=MAP-ICP)

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23
Q

Pressure Management

A
20-30% develop acute hydrocephalus
Most require shunting
Clip ligation or coiling for aneurysm
Prevent and treat vasospasm (peak day 5-7)
Seizure prophylaxis may be indicated
24
Q

ASA Clinical Practice Guideline for Stroke

A
Algorithm A  B  C
Key points of ?prevention of complications  minimize impairments  and maximize function.?
Secondary prevention of another stroke
Early assessment and intervention
Standardized evaluation and tools
EBP ? based interventions
Multidisciplinary team
Pt and family ed and team
Community resources
25
Physical Therapy Examination - Review
History and systems review Identify problem areas individual therapist Make hypotheses Test your hypotheses with your examination task analysis tests and measures Clinical Impression Link participation difficulties with activities and impairments Combined with the history what is the prognosis for change? How do you prioritize your interventions? Set goals that address impairments in body structure and function AND activities
26
Stroke Examination
``` History Age and living situation Participation and Activity level Type and location of stroke How long since stroke Medications Blood pressure parameters Co-morbid pre-morbid conditions ``` ``` Systems Review Neuromuscular Musculoskeletal Cardiopulmonary/Vascular Cognition/Communication Integumentary Genitourinary Gastrointestinal Endocrine ```
27
Neuromuscular Impairments of Body Structure/function
``` Lack of adequate force production Lack of adequate timing Abnormal synergistic movement patterns Muscle imbalance Lack of adequate motor planning Decreased postural control Sensory-Perceptual visual deficits ```
28
Risk of falls: <30 days post CVA
``` <30 Berg Balance Score Apraxia Cognitive deficits Low Functional Independence Measure (FIM) scores Predictive of increased fall rates ```
29
Risk of falls: >6 months post CVA community dwelling
Self-reported persistent balance problems while dressing is predictive of falls
30
Fall predictors in older adults
Incontinence Medications History of falls These factors are not predictive of falls post CVA
31
Apraxia
Loss of ability to execute skilled or learned movement patterns on command in the absence of weakness sensory loss comprehension difficulty abnormality of tone or posture or intellectual deterioration.
32
Ideational apraxia
Planning of a movement fails | Patient is unable to conceptualize how a movement pattern must be organized.
33
Ideomotor Apraxia
Plan for the movement is intact but the execution fails. Damage within pathways connecting the areas in which the plan is conceived to those responsible for innervating the motor plan
34
Aphasia
Impairment of language associated with damage to the language dominant hemisphere. Nearly always involves damage to the left fronto-temporal and/or temporo-parietal regions. May affect verbal expressive output fluency comprehension naming reading writing and repeating.
35
Global aphasia
commonly associated with a large lesion in the frontal temporal and parietal lobes of the brain causing an almost total reduction of all aspects of spoken and written language
36
Broca's (expressive motor) aphasia
loss of the ability to produce language (spoken or written)
37
Receptive aphasia also known as Wernicke?s aphasia fluent aphasia or sensory aphasia
loss of ability to understand language (spoken or written)
38
Hemi-Neglect
Failure to attend to respond to and/or report stimulation that is introduced contralateral to the lesion. Most often seen with non-dominant parietal association area lesions. Affects contralesional side. Persistent neglect is a negative functional outcome predictor.
39
Intrapersonal Hemi-Neglect
Contralateral hemineglect of patient?s own body associated with anosagnosia (denial of deficit)
40
Peripersonal hemi neglect
Hemispatial neglect of contralateral stimuli within reaching distance.
41
Extrapersonal hemi neglect
Hemispatial neglect of contalateral stimuli beyond reaching distance.
42
Dysarthria
Difficulty producing speech
43
Dysphagia
Difficulty swallowing Difficulty eating Dealing with secretions
44
Stroke Tests and Measures
``` 6MWT 10 m walk Modified Ashworth Scale Berg Balance Test Functional Reach Test Dynamic Gait Index Fugl-Meyer (Motor ) Orpington Prognostic Scale Postural Assessment Scale for Stroke Stroke Impact Scale Tardieu Spasticity Scale Action Research Arm Test (ARAT) Chedoke-McMasters ```
45
Fugl-Meyer Motor scale
100 point motor domain is reliable valid and responsive to clinical change
46
Chedoke-McMaster Stroke Assessment
Measure of impairments and disability level Impairments in 6 dimensions: shoulder pain postural control arm hand leg foot measured on a 7 point scale following Brunnstrom stages Disability measured by gross motor function and walking measured on same 7 point scale as FIM
47
Postural Assessment Scale for Stroke Patients (PASS)
``` Maintaining a Posture (0-3) Sitting without support with feet on floor Standing with support Standing without support Standing on non-paretic leg Standing on paretic leg Changing Posture (0-3) Supine to affected side lateral Supine to non-affected side lateral Supine to sitting EOT Sitting on edge of table to supine Sitting to standing Standing to sitting Standing picking up pencil from floor ```
48
Stroke Impact Scale (SIS)
Questionnaire 5 point scale - Not Difficult at all to Extremely Difficult Physical problems Memory and thinking Mood and emotions Communication Activities in a typical day Mobility in home and community Hand function Ability to participate in usual meaningful activities On a scale of 0=100 how much have you recovered?
49
Action Research Arm Test (ARAT)
Total score 0-57 Scored 0-3 on each item Minimal clinical important difference (MCID) 5.7 points
50
Additional Tests and Measures
``` Glasgow Coma Scale (GCS) NIH Stroke Scale (NIHSS) Montreal Cognitive Assessment (MOCA) Modified Tardieu Scale Functional Independence Measure(FIM) ```
51
Glasgow Coma Scale (GCS)
EYE OPENING None = 1 Even to supra-orbital pressure To pain = 2 Pain from sternum/limb/supra-orbital pressure To speech = 3 Non-specific response not necessarily to command Spontaneous = 4 Eyes open not necessarily aware MOTOR RESPONSE None = 1 To any pain; limbs remain flaccid Extension = 2 Shoulder adducted and shoulder and forearm internally rotated Flexor response = 3 Withdrawal response or assumption of hemiplegic posture Withdrawal = 4 Arm withdraws to pain shoulder abducts Localizes pain = 5 Arm attempts to remove supra-orbital/chest pressure Obeys commands = 6 Follows simple commands VERBAL RESPONSE None = 1 No verbalization of any type Incomprehensible = 2 Moans/groans no speech Inappropriate = 3 Intelligible no sustained sentences Confused = 4 Converses but confused disoriented Oriented = 5 Converses and oriented TOTAL (3?15): _______
52
NIH Stroke Scale (NIHSS)
``` Time Intervals: Baseline 2 hours post treatment 24 hours post onset 7-10 days 3 months other Scored 0 1 2 scale with 0 = normal Level of Consciousness Best Gaze Visual Facial Palsy Motor Arm Motor Leg Limb ataxia Sensory Best Language Dysarthria Extinction and Inattention (neglect) ```
53
Montreal Cognitive Assessment (MOCA)
MOCA Scale 0-30 Consider language difficulties
54
Modified Tardieu Scale
Velocity One = V1 Slow movement Goniometric measurement at this joint angle Velocity Two = V2 Fast movement Goniometric measurement at this joint angle May provide more precision in documenting amount of spasticity and amount of contracture
55
Functional Independence Measure (FIM)
``` 20 functional items measured on 7 point scale: 7 = Independence 6= Modified Independence 5= Supervision (subject does 100%) 4= Minimal Assist (subject does 75%) 3= Moderate Assist (subject does 50%) 2= Maximal Assist (subject does 25%) 1= Total Assistance (subject does < 25%) ```