10. Dosimetry Flashcards
What is ionizing radiation?
radiation with high enough energy to produce ion pairs directly or indirectly (+ ion, - free electron) while absorbed in the matter.
It includes corpuscular radiations and high-energy electromagnetic radiations (X-rays and γ-rays).
2 types of ionizing radiations
(1) Direct ionization (in case of charged particles)
2) Indirect ionization (in case of uncharged particles and high-energy electromagnetic radiation
2 Examples of direct ionization
Alpha
Beta
2 example of indirect ionization
Gamma
X-rays
The part of the ionizing radiation that is absorbed in a living organism leads, via different processes (physical, radiochemical, molecular biological), to macroscopic biological changes or damage, the severity of which depends on the parameters listed below:
List 4 parameters
(1) Type of radiation
(2) sensitivity of the organ or part of the body that received the radiation
(3) the received dose (D)
(4) the time course of the received dose
What is direct effect?
It occurs when the ionizing radiation is absorbed in biologically important macromolecules (e.g., DNA), and causes damage there directly.
What is indirect effect?
It occurs when the ionizing radiation is absorbed in water, the largest constituent, by quantity, of the organism, and induces the formation of free radicals (∙H, ∙OH, etc.).
=> These highly reactive free radicals then interact with the biologically important macromolecules.
What is deterministic effect?
the probability of radiation damage increases abruptly above the threshold dose.
Above this dose level, the severity of the damage is proportional to the dose.
Erythema and cataract (transparency loss of the eye lens) are typical deterministic effects.
What is stochastic effect?
the probability of radiation damage is proportional to the dose (a threshold dose cannot be defined).
Genetic disorders and some forms of cancer (which are a consequence of mutations) are caused by this “random” effect.
What is the role of radiation protection?
To prevent the deterministic effects
To decrease the risk of the stochastic effects to an acceptable level in the proximity of the radiation sources (therapeutic and diagnostic X-ray devices, closed and open radioactive preparations).
What is absorbed dose?
the amount of energy absorbed per unit mass
∆E - energy absorbed by mass ∆m
Unit - 1Gy = 1 J/kg
Formula for exposure
Where ∆q is the positive charged produced in air of mass ∆m by ionization
Unit - C/kg
2 types of rays that EXPOSURE formula is valid for
X-rays
Gamma rays
The role of effective dose equivalent (E)
It expresses the biological damage of the individual tissue or organ
formula for effective dose
the equivalent dose, which is multiplied by a tissue weighting factor (wT) characteristic for the tissue sensitivity towards radiation damage
Unit- sievert
The role of dose rate
It characterizes the strength of the ionizing radiation
What is dose rate in case of constant-intensity radiation?
The ratio of the dose and the duration of irradiation
According to their principle of operation, what are 2 main groups of dosimeters?
(1) Gas-ionization detectors
(2) Solid-state detectors
1 example of gas-ionization detectors
Ionization chamber
2 examples of solid-state detectors
Thermoluminescent dosimeter
Scintillation dosimeter
In case of dose measurement, the (1) Voltage U produced by the accumulated charge Q on _____ C is (3) proportional to the total amount of the _____
(2) Capacitor
(3) proportional
(4) separated charges
In case of dose rate measurement, instead of the capacitance, the potential drop is measured on a large ______ which is (2) Proportional to the (3)_____ that flows through per unit time, thus it is (4) Proportional to the (5)_____
(1) Resistance R
(2) Proportional
(3) Charge Q
(4) Proportional
(5) Exposure dose rate (X/t)
What is ionization chamber?
It measures radiation dose from the quantity of charges produced in a mass of air between the charged plates of a capacitor.
As charges move towards the electrodes, they produce an electric current proportional to the dose rate.
The change in capacitor charge is proportional to the dose
3 types of ionization chambers
(1) Thimble ionization chamber
(2) Pocket chamber dosimeter
(3) GM-tube