Anticoagulants

Question 1

MOA Heparin & low molecular weight heparin

enoxaparin, Lovenox

Answer 1

Prevents clotting by activating Antithrombin- indirectly inactivates thrombin & factor Xa

Question 2

Side Effects of ALL anticoagulants

Answer 2

BLEEDING

Question 3

Nursing Considerations of Heparin

Answer 3

Starts working Quickly

Question 4

Adverse effects of Heparin

Answer 4

Bleeding, hematoma, anemia, thrombocytopenia

Question 5

Indications of Enoxaparin (Lovenox)

Answer 5

given prophylaxis & treatment

Question 6

Adverse Effects of Enoxaparin (Lovenox)

Answer 6

bleeding, thrombocytopenia

can cause HIT

Question 7

MOA of Warfarin (Coumadin)

Answer 7

prevents the synthesis of four coagulation factors

VII, IX, X, prothrombin

Question 8

Adverse Effects of Warfarin (Coumadin)

Answer 8

bleeding, lethargy, muscle pain, purple toes

Question 9

MOA of Apixaban (Eliquis) & Rivaroxabean (Xarelto)

Answer 9

direct inhibitor of factor Xa

Question 10

Adverse effects of Apixaban (Eliquis) & Rivaroxabean (Xarelto)

Answer 10

bleeding, hematoma, dizziness, rash, gastrointestinal distress, peripheral edema

Question 11

Aspirin (as anti-platelet)

Answer 11

blocks prostaglandin synthesis through the COX enzyme pathways

Question 12

Side effects of Aspirin

Answer 12

n/v, drowsiness/confusion, bleeding

Question 13

MOA of Clopidogrel (Plavix) & Ticagrelor (Brilinta)

Answer 13

antiplatelet ADP inhibitor

Question 14

Side effects of Clopidogrel & Ticagrelor

Answer 14

chest pain, edema, flu-like symptoms, abdominal pain, diarrhea, nausea, epistaxis, rash, pruritus

Question 15

Thrombin Inhibitors

Answer 15

inhibit thrombin (factor lla)

Question 16

Adverse Effects of thrombin inhibitors

Answer 16

bleeding