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NUR 325 Fundamentals of Pathopharmacology > Pain > Flashcards

Flashcards in Pain Deck (17)
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1
Q

MAO of tramadol (Ultram)

A

Binds weakly to mu opioid receptors

Inhibits reuptake of both norepi and serotonin

2
Q

Adverse effects of tramadol

A

drowsy, dizziness, headache, nausea, constipation, respiratory depression
Rare: Seizures

3
Q

MAO of gabapentin (Neurontin) & pregablyn (Lyrica)

A

to spontaneously suppress neuronal firing

4
Q

Adverse effects of gabapentin & pregablyn

A

drowsy, dizzy, visual problems

5
Q

Type of NSAIDS

A

aspirin (ASA), ibuprofen (advil), naproxene (Aleve), ketorolac (Toradol), celecoxib (Celebrex)

6
Q

MOA of NSAIDS

A

Anti-prostaglandins

blocks key enzyme: cyclooxygenase (COX)- an enzyme that is crucial to the production of prostaglandins

7
Q

Adverse Effects of NSAIDS- ASA, ibuprofen, naproxen

A

GI upset, stomach ulcers, GI bleeding, rash, edema, kidney failure, increases in BP, inhibits platelet aggregation, SOA in asthma patients

8
Q

Adverse Effects of Celecoxib (Celebrex)

A

Serious Cardiovascular thrombotic events

9
Q

NSAIDS Cardiovascular Risk

A

NSAIDS cause an increased risk of serious cardio thrombotic events, MI, stroke and increase risk for cardiovascular disease

10
Q

NSAIDS Gastrointestinal Risk

A

Increased risk of serious GI bleeding, ulcerations and perforation of the stomach or intestines which can be fatal

11
Q

Aspirin Adverse Effects

A

n/v, seizures, cerebral edema

chronic- tinnitus/hearing losst

12
Q

Reye’s Sydrome for kids

A

NO ASPIRIN

13
Q

Ketorolac (Toradol)

A

Post-Op setting to reduce pain and inflammation

14
Q

Side Effects of Toradol

A

GI ulcers, high risk of renal dysfunction

15
Q

MOA of Acetaminophen (Tylenol)

A

Unknown

16
Q

Adverse effects of Acetaminophen

A
hepatic necrosis (acture) liver failure
Look for - Jaundice
17
Q

MAO of IV Tylenol- Ofirmev

A

unknown