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Pharmacology > Pharm 2 > Flashcards

Pharm 2 Flashcards

1
Q

Where does spironolactone act?

A

Distal DCT

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2
Q

What is a potassium sparing diuretic

A

Spironolactone amloride

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3
Q

Overdose of which initlaly causes resp alkalosis and then metabolic aciosis

A

Aspirin

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4
Q

Metabolised by CYP3A4

A

Simvastatin

CICOSPORIN

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5
Q

Inhibits CYP3a4 enzyme

A

ERYTHROMYCIN ( MACROLIDES INC CLARITHROMYCIN LESSER EXTENT)

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6
Q

SUBJECT TO ACYLATION IN LIVER

A

Izoniazide

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7
Q

Slow acetylor status

A

causes high isoniazid which ccauses peroperhal neuropathy

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8
Q

Rapid acetylor status

A

causes high levels of isonizid metabolite which is invreasing hepatotoxic

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Pharmacology (5 decks)

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