Week 3 - Cardiac Flashcards

1
Q

what are a few key terms for ischemic chest pain

A
Occur in both exertion or at rest.
does not alter due to change in position or posture
Not exacerbated by movement or deep inspiration.
Described as
Tightness
Pressure
Heaviness
Indigestion
Ache
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2
Q

what are topical locations of angina

A

Chest - central or left sided, may involve epigadtrium
arms - left arm may be both
throat

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3
Q

what are the 3 radiation areas of a typical angina

A

jaw
back
shoulders

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4
Q

key points of typical angina

A

radiation to arms or neck increases the likelihood that the pain is myocardial ischemia. not all patients presents typical
symptoms, especially women

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5
Q

what are the features of myocardial ischaemia

A
shortness of breath
sweating
nausea
vomiting
palpitations
dizziness
weakness
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6
Q

what is “Chronic” Stable Angina

A
  • Usually due chronic narrowing of the coronary artery.
  • Blood flow may be adequate to supply the myocardium during periods of rest and low activity resulting in no pain
  • Inadequate blood supply during conditions of increased myocardial oxygen demand (exercise, stress) pain
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7
Q

what is stable angina

A
Onset/pattern of pain is often predictable
Occurs in response to activities that increase HR and BP (myocardial workload)
  - exercise
  - sexual activity
  - emotional stress 
Often worse 
  - early in the morning
  - after a heavy meal
in cold weather
Usually resolves within 2-10 minutes
  - rest 
  - GTN
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8
Q

how should chronic stable angina be managed

A
Pharmacotherapy
 - Nitrates
    >Short and long acting
- Antiplatelet therapies
  > Aspirin
  > Clopidogrel
- Calcium Channel Blockers
- Beta Blockers
- Perhexiline
Revascularization
  - Percutaneous Coronary Angioplasty (PTCA) +/- intracoronary stent
  - Coronary Artery Bypass Surgery (CABG)
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9
Q

what are the signs and key points of Stable angina turning into unstable angina

A

Signs that stable angina may becoming unstable:
more frequent
more severe
lasting longer
not responding to rest/GTN
occurring with less exertion
occurring at rest
waking the patient from sleep.
Key Points
Stable angina can progress to unstable angina.
Unstable angina is associated with greater risk of death than stable angina

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10
Q

symptoms of Acute Myocardial Infarction (AMI)

A
Pain is usually prolonged and severe
Often associated with fear, anxiety, distress
May occur with no prior warning
May be preceded by unstable angina 
May occur at rest
May be associated with a precipitating factor, such as 
vigorous physical exercise
emotional stress
medical/surgical illness
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11
Q

what are the major presenting symptoms of Atypical AMI

A
Some patients with AMI do not experience angina pain
Known as silent ischaemia
The major presenting symptoms in these patients include 
dyspnoea
diaphoresis
nausea/vomiting
pre-syncope/syncope
sudden loss of consciousness
confusion
profound weakness
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12
Q

key points of Acute Myocardial Infarction

A

Estimated that 50% of all AMI deaths occur before the person reaches hospital
Pre-hospital goals:
- Reduce mortality
>basic life support
>advanced life support
>early defibrillation
Minimise delay from symptom onset to reperfusion therapy

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13
Q

how is Acute coronary syndrome diagnosed

A

Diagnosed on the basis of ECG/cardiac enzymes
Unstable Angina
Not total occlusion of epicardial coronary artery
No ST elevation on the ECG
Cardiac enzymes (troponin/CK) normal
Non-ST elevation myocardial infarction (NSTEMI)
Not usually total occlusion of epicardial coronary artery
No ST elevation on the ECG
Elevated cardiac enzymes (troponin/CK)
ST elevation myocardial infarction (STEMI)
associated with occluded epicardial coronary artery
ST elevation on the ECG
Elevated cardiac enzymes (troponin/CK)

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14
Q

what key notes are to be asked about patient history in regards to cardiac diseases

A
Chest pain assessment (watch the video on learnonline)
Past illnesses
Allergic reactions
Medication history
Alcohol, drug and tobacco habits
Social history
Cardiovascular risk factors
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15
Q

what are the non-modifiable risk factors

A

Age
CVD predominantly affects middle aged and older Australians – but is becoming more common in younger Australians (male and female)
Gender
more common in men than women, as women are thought to be protected by oestrogen prior to menopause
women have equal risk to men by age 65.
Family history of CVD
The risk of CVD is increased if a first degree relative <60 years of age is diagnosed with heart or blood vessel disease.

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16
Q

what are the modifiable risks

A
Smoking
Hypertension
Diabetes
Physical inactivity
Poor nutrition
Alcohol consumption
Psychosocial factors
17
Q

what are the psycosocial risk factors

A
Psychosocial factors associated with risk for CVD include:
depression
social isolation
lack of quality social support
poor personal economic resources
lower levels of education
poor living and working conditions
stress
limited access to health care and social services
18
Q

what can be monitored by a 12-lead ECG

A
Rate
Rhythm
Ischaemic changes
ST segment elevation
ST segment depression
T-wave abnormalities
Q-waves
Conduction abnormalities
Bundle branch block
Axis deviation
Left ventricular hypertrophy
Incremental Leads
Posterior leads (v7,v8,v9)
Right ventricular leads (v4R)
19
Q

what are the initial blood test that are taken when

A
Blood tests
Serum troponin I or T levels 
CK-MB if troponin not available
Creatine kinase (CK)
Full blood count
Serum creatinine
eGFR 
Electrolytes
serum lipid levels within 24 hours
blood glucose level
20
Q

Cardiac Imaging

A
Chest x-ray
heart
lungs
should not delay reperfusion treatment
Radionuclide Studies
thallium-201
technetium-99m sestamibi
positron emission tomography
echocardiography
21
Q

Angina: Treatment Goals

A
Relieve angina symptoms
 increase myocardial O2 supply
 decrease myocardial O2 demand 
Decrease the risk of myocardial infarction
Prolong survival
Reduce disease progression
22
Q

Unstable angina pectoris Management

A
Oxygen therapy if required (O2 sat below 93%)
Cardiac Monitoring
Arrhythmias
ST-segment and T-wave changes
Rest
Reversal of precipitating factors 
hypertension
anaemia
stress
Pharmacotherapy
Nitrates
Anticoagulant
Antiplatelet
Calcium Channel Blockers
Beta Blockers
Perhexiline
Revascularisation
Percutaneous Coronary Angioplasty (PTCA) +/- intracoronary stent
Coronary Artery Bypass Surgery (CABG)
23
Q

Acute Myocardial Infarction maagement

A

Pathogenesis is the same as that of UAP and so the treatment is similar BUT:
Time is muscle!!!
Urgent revascularisation (opening the artery) is required
PTCA
Fibrinolytic therapy

24
Q

STEMI: Primary therapeutic strategies

A
Initial treatment
I.V. access
IV nitrates
antiplatelet therapy
anticoagulation
O2 therapy
aspirin
morphine
25
Q

STEMI: Reperfusion strategies

A
Percutaneous transluminal coronary
angioplasty (PTCA)
\+ Clopidogrel
\+/- GPIIb/IIIa agents (abciximab)
treatment of choice 
if provided promptly
by a qualified interventional cardiologist
In an appropriate facility

Fibrinolysis (thrombolytic therapy)
should be considered early if PCI is not readily available
particularly in rural and remote areas.
not routinely recommended in patients who present more then 12 hours after symptom onset and are asymptomatic and haemodynamically stable.

Coronary artery bypass graft (CABG) surgery
suitable anatomy and are not candidates for fibrinolysis or percutaneous coronary intervention (PCI)
cardiogenic shock
in association with mechanical repair.