Antimalarials

Question 1

Both erythrocytic and exoerythrocytic

Answer 1

CYCLOGUANIL

Question 2

For multi drug resistant forms of Plasmodium falciparum

Answer 2

Mefloquine

Question 3

Giardiasis, tapeworm and malaria, leishmaniasis

Answer 3

Quinacrine

Question 4

Highly supressive (P. vivax and P. falciparum)

Answer 4

Amiodaquine

Question 5

DOC for erythrocytic falciparum

Answer 5

Chloroquine

Question 6

Reserved for malarial strains resistant to other agents

Answer 6

Quinine

Question 7

Only for exoerythrocytic stages of malaria

Answer 7

Primaquine

Question 8

Anti inflammatory (RA and discoid lupus)

Answer 8

Chloroquine

Question 9

Adverse effects of Quinine

Answer 9

Cinchonism, Abortifacient

Question 10

Acute P. vivax attack

Answer 10

Chloroquine

Question 11

Curative (P. falciparum)

Answer 11

Amiodaquine

Question 12

Radical cure of the P. vivax & ovale, Gametocidal for all species

Answer 12

Primaquine

Question 13

Common structural feature: quinoline ring, or a “quinoline with an additional benzene added” (an acridine ring)
=None except the cinchona alkaloids has a quinuclidine ring

Answer 13

ANTIMALARIALS

Question 14

Classes of Cinchona alkaloids

Answer 14

Quinine

Question 15

Classes of 7 CHLORO 4

AMINOQUINOLINES

Answer 15

Chloroquine, Amiodaquine

Question 16

Classes of 8 AMINOQUINOLINES

Answer 16

Primaquine

Question 17

Classes of 9 AMINOACRIDINES

Answer 17

Quinacrine, Mefloquine