Group 8 - Oxytocin (Pitocin) Flashcards
Oxytocin (Pitocin)
Drug Class?
Oxytocin (Pitocin) Drug Class:
- Pituitary Hormone
- Uterine Stimulant
Oxytocin (Pitocin)
Mechanism of Action (MOA)?
Oxytocin (Pitocin) MOA:
- Binds to oxytocin receptors on surface of uterine smooth muscles
- Increases force and frequency of uterine contractions
Oxytocin (Pitocin)
Indications?
Oxytocin (Pitocin) Indications:
- Postpartum hemorrhage due to uterine atony (loss of muscle tone)
Oxytocin (Pitocin)
Contraindications?
Oxytocin (Pitocin) Contraindications:
- Hypersensitivity
Oxytocin (Pitocin)
Adverse Reactions?
Oxytocin (Pitocin) Adverse Reactions:
- CV: Shock, Tachycardia, Dysrhythmias
- Resp: Anaphylaxis
- GI: Nausea and Vomiting
- Other: Clotting disorders, electrolyte disturbances
Oxytocin (Pitocin)
Adult Dose?
Oxytocin (Pitocin) Adult Dose:
- 10 - 20 USP units added to 1,000 mL NS or LR and run at a rate to control uterine atony
- Or, 10 USP units IM after delivery of the placenta
Oxytocin (Pitocin)
Pediatric Dose?
Oxytocin (Pitocin) Pediatric Dose:
- Not Applicable
Oxytocin (Pitocin)
Onset of Action?
Oxytocin (Pitocin) Onset of Action:
- Seconds
Oxytocin (Pitocin)
Peak Effects?
Oxytocin (Pitocin) Peak Effects:
- Variable
Oxytocin (Pitocin)
Duration of Action?
Oxytocin (Pitocin) Duration of Action:
- 1 hour after discontinued
Oxytocin (Pitocin)
AZ Drug Box Minimum Supply?
Oxytocin (Pitocin) AZ Drug Box Minimum Supply:
- Optional: 10 units
Oxytocin (Pitocin)
Special Notes?
Oxytocin (Pitocin) Special Notes:
- Postpartum hemorrhage is defined as blood loss in excess of 500 mL at delivery and during the first 24 hours after delivery
- All blood seen at delivery is the mother’s unless there is a spill of cord blood or trauma to the placenta
- Do Not Use if solution is discolored or contains a precipitate
- Fundal massage is also indicated to remove clot formation and stimulate uterine contraction
