Adjunctive therapies: stress ulcer prophylaxis

Question 1

Who is at greates risk to develop stress ulcer?

Answer 1

• severe sepsis
• coagulopathic
• mechanically ventilated - > 48hrs
• hypotesice

Question 2

What prophylaxis is used for stress ulcer ?

Answer 2

• H2-r antagonist - ranitidine > effective than sucralfate
• PPI - omeprazole
  benefits weight against potential effect of increased gastric pH and dev of infectious complications like HAP / C - diff