Robinul (Glycopyrrolate)

Question 1

Robinul (Glycopyrrolate) class

Answer 1

Anticholinergic

Question 2

Robinul (Glycopyrrolate) MOA

Answer 2

Blocks effects of ACh at parasympathetic sites

Reduces rate of salivation by preventing stimulation of ACh receptors

Question 3

Robinul (Glycopyrrolate) dosage

Answer 3

7-15 mcg/kg

Question 4

Robinul (Glycopyrrolate) characteristics

Answer 4

O: IV 2 min
IM/subq: 15-30 min

P: 30-45 min

D: 2-4 hrs

Question 5

Robinul (Glycopyrrolate) E/M

Answer 5

85% urine, 15% feces

Question 6

Robinul (Glycopyrrolate) considerations

Answer 6

Unlikely to pass BBB, placenta, or GIT due to ionization

No likely to cause anticholinergic syndrome

Used for brady (HR 50’s) w/o causing tachy

Push over 2-5 min