eosinophilic fasciitis

Question 1

epidemiology

Answer 1

female and caucasian predominance, 40-60 yo

Question 2

what is the main association?

Answer 2

a/w strenuous activity/exercise (1/3 of patients). other triggers include trauma, borreliosis, statin use

Question 3

clinical features

Answer 3

symmetric edema/induration & PAINFUL extremities with eosinophilia on CBC. spares hands/feet/face. “dry river bed” or “groove sign” - veins trapped within indurated skin

Question 4

dermpath

Answer 4

massive thickening and fibrosis of deep fascia, lymphoplasmacytic infiltrate

Question 5

treatment

Answer 5

1. systemic steroids (or plaquenil, cyclosporine, dapsone, MTX, etc)
2. physical therapy to prevent contractures