MCTD Flashcards
1
Q
what defines MCTD
A
2 of the any of the following: SLE, DM/PM, scleroderma, or RA
2
Q
what is the targeted autoAB
A
anti-U1RNP
3
Q
what is the HLA a/w
A
HLA-DR4
4
Q
tx
A
prednisone + MTX if severe arthritis (must use with caution in MCTD patients given risk of pulmonary fibrosis)
5
Q
how many of these patients will develop into 6 distinct CTD
A
40%
6
Q
what is the ANA nuclear pattern?
A
speckled
