Heparin

Question 1

Presentation

Answer 1

5000 units in 5ml

Question 2

Indications

Answer 2

STEMI

Question 3

Contraindications

Answer 3

1. Known hypersensitivity
2. Actively bleeding
3. Oral anticoagulants
4. Bleeding disorders
5. History of heparin induced thrombocytopenia
6. Severe hepatic impairment/disease
7. Recent trauma or surgery <3weeks

Question 4

Precautions

Answer 4

1. Renal impairment

Question 5

Side effects

Answer 5

1. Bleeding
2. Bruising and pain at injections site
3. Hyperkalaemia
4. Thrombocytopenia

Question 6

IM effects

Answer 6

Onset - Immediate

Duration - 3-6hrs

Question 7

Pharmacology

Answer 7

Heparin is an anticoagulant which inactivates clotting factors IIa (thrombin) and Xa by binding to antithrombin III