M Gen Flashcards
Risk factors for m gen
Young
Smoking
Non white
Increasing no of sex partners
M gen infection can cause….?
NSU (acute, recurrent, persistent)
PCB cervicitis, endometritis and PID
Preterm birth and miscarriage
Diagnosis cervicits what signs Sx
PCB
Mucopurelent d/c
PMNLs >5
Cervical friability
When to defo test for m gen
PID
NSU
Partner pos for m gen
Consider for proctitis, EO and cervixitis
How to test for m gen in men and women
Men FVU
Women VVS
When have sex following M gen diagnosis?
14/7 post starting Rx and until Sx resolved
TOC for all
Drugs for M gen and routine NSU, cervix it is
Doxy 100mg bd for 7/7 then extended azith if unknown sensitivity or not resistant
If macrolides resistant or azith failed - give moxifloxacin 400mg od for 10/7
Max time between doxy and giving azith for m gen
2 weeks post end of doxy
If not then repeat course
If doxy given first line for M gen then what to do depending on resistance?
If not macrolides resistant- give extended azith
If macrolides resistant give moxi 10/7
TOC 5/52
If extended azith given first line for m gen (doxy intolerant) what to do with resistance results?
If macrolides not resistant - toc 5/52
If macrolides resistant - give moxi 10/7
Toc 5/52 for all
Complicated infection of m gen (PID eo) and Rx
Moxi 14/7 400mg od
If m gen pos or partner m gen pos
Pn for m gen
Only current partners test and treat if pos
Alternative m gen Rx
Doxy 100mg bd for 7/7 then pristinamycin 1g qds for 10/7
Pristinamycin 1g qds for 10/7
Doxy 100mg bd for 14/7
Minocycline 100mg bd for 14/7
Pregnancy, breastfeeding and m gen
Azith ok No doxy No moxi Azith low levels in milk Increased risk of preterm and spont abortion
Side effects of moxi and azith
Gi
Prolonged qt
Stop if get tendon muscles problems
