Pharmacogenomics (PK Week 8)

Question 1

HLA-B genotyping is recommended when starting which of the following HIV antiviral medications to avoid potentially life-threatening hypersensitivity reactions?

Answer 1

Abacavir

Question 2

CYP2D6 polymorphism can affect

Answer 2

Toxicity

Question 3

Which gene predicts adverse reaction to simvastatin?

Answer 3

SLCO1B1