dementia

Question 1

dementia presentation

Answer 1

Cognitive imapirment - ofetn memory problems, language, praxis, perception , executive function
Functioal imapirment - problems w basic or instrumental activities of daily living
Behavious and psychological symptoms of dementia (BPSD) - eg. psychosis, pacing, shouting, sexual disinhibition, aggression
Neurological symps - eg. seizure (10-20%)

Question 2

Alzheimers key clinical features

Answer 2

early memory loss, gradual onset and progression

Question 3

vascular dementia key clinica features

Answer 3

focal neurology, evidence of cerebrovascular disease, may be stepwise progression

Question 4

Mixed key clinical features

Answer 4

features of both alzheimers and vasc dementia

Question 5

Why are antipsychotics contraindicated in Lew Body dementia

Answer 5

can cause parkinsonian reaction

Question 6

lewy body dementia key clinical features

Answer 6

fluctuating cognition, visual hallucinations, parkinsonism

Question 7

frontotemporal dementia key clinical features

Answer 7

change in behaviour and conduct, dietary chnages, emotional blunting, prominent language probelms

Question 8

parkinsons w dementia key clinical features

Answer 8

diagnosis of PD prior to dementia onset, dementia features similar to Lewy body

Question 9

alzheimers pathophysiology

Answer 9

beta amyloid plaques between neurons and neurofibriliary tau tangles within neurons

Question 10

Vascular dementia pathophysiology

Answer 10

multiple small infarcts or single strategic infarct

Question 11

lewy body dementia pathophysilogy

Answer 11

deposition of lewy bodies - alpha synuclein - in neurons

Question 12

mild cognitive impairment defintion

Answer 12

impairment on standardised test but no functional impact

Question 13

sunjective cognitive impairment defintion

Answer 13

no deficit on standardised test but complains of congitive problems