LEUKOCYTE MORPHOLOGICAL ABNORMALITIES (LA)

Question 1

-THUMBPRINT APPEARANCE FRAGILE

Answer 1

BASKET/SMUDGE CELL

Question 2

-Associated with Degenerated nucleus or ruptured cell in form or basket/smudge

Answer 2

BASKET/SMUDGE CELL

Question 3

-LYMPHOCYTES that appear during smear preparation

Answer 3

BASKET/SMUDGE CELL

Question 4

ARTIFACT→ appear at the end of smears

Answer 4

BASKET/SMUDGE CELL

Question 5

-Hair like cytoplasmic projections surrounding the nucleus

Answer 5

HAIRY CELL

Question 6

(fried-egg appearance)

Answer 6

HAIRY CELL

Question 7

-TRAP (Tartrate-resistant acid phosphatase stain) positive [only cell positive]

Answer 7

HAIRY CELL

Question 8

-Nearly all blood cells contain 7 non-erythroid

Answer 8

HAIRY CELL

Question 9

Lymphocyte with convoluted nucleus/brain- like nucleus

Answer 9

SEZARY CELL

Question 10

Presence indicates LEUKEMIC PHASE of mycosis fungoides (sezary syndrome) [abnormal T lymphocyte]

Answer 10

SEZARY CELL

Question 11

Abnormal lymphocyte with an “owl’s eye appearance”

Answer 11

REED-STERNBERG/RS CELLS

Question 12

Pathognomonic sign for Hodgkin’s lymphoma[one if the deadliest] Clinical significance: Hodgkin’s Lymphoma

Answer 12

REED-STERNBERG/RS CELLS

Question 13

Lymphocyte with a clover leaf like nucleus

Answer 13

RIEDER CELL

Question 14

-Abnormal plasma cell with red to pink cytoplasm

Answer 14

FLAME CELL [abnormal plasma

Question 15

-Associated with increased Immunoglobulins (usually IgA);

Answer 15

FLAME CELL [abnormal plasma

Question 16

-Inclusion: Russel bodies (individual bodies of Immunoglobulin)

Answer 16

FLAME CELL [abnormal plasma

Question 17

Waldenstrom’s macroglobulinemia

Answer 17

FLAME CELL [abnormal plasma

Question 18

Abnormal plasma cell with small colorless vacuoles AKA Berry, Mott, Morula Ce

Answer 18

GRAPE CELL [abnormal plasma cell]

Question 19

Large protein globules giving appearance of grapes: “Honeycomb appearance”

Answer 19

GRAPE CELL [abnormal plasma cell]