Chapter 8

Question 1

what is nonneoplastic disease of bone

Answer 1

• not neoplasms

- 3 main disease states: fibrous dysplasia, paget disease, osteomalacia

Question 2

what is fibrous dysplasia

Answer 2

• replacement of bone with abnormal fibrous connective tissue
• interspersed
• various calcifications
• benign
• characteristic ground glass appearance

Question 3

what are the 2 types of fibrous dysplasia

Answer 3

• monostatic (one bone affected)

- polyostatic (multiple bones affected) – causes unknown, abnormal mesenchymal cell function

Question 4

what is monostatic fibrous dysplasia

Answer 4

• most common (85% of cases)
• single bone
• max/mn/ribs/long bone
• children
• young adults
• bulging buccal plate (tipping, displacement, malocclusion)

Question 5

what is polyostatic fibrous dysplasia

Answer 5

• more than one bone
• children, female most common
• skull, clavicles, long bones
• bowing of bones
• cafe au lait spots

Question 6

what are clinical and radiographic features of polyostotic fibrous dysplasia

Answer 6

• painless enlargement
• except extreme cases
• progressive
• unilateral
• ground glass appearance

Question 7

what is diagnosis and treatment for polyostotic fibrous dysplasia

Answer 7

• dx: characterized by cellular fibrous connective tissue interspersed with irregularly shaped bony trabeculae. in fibrous dysplasia, radiographic changes blend into the surrounding normal bone
• tx: surgical recontouring of bone for cosmetic reasons