Neurodegenerative Disorders Flashcards
1
Q
Define Neurodegenerative disease?
A
Progressive Neuronal loss, usually of late onset and unknown aetilogy
2
Q
What do we call clearly inherited neurodegenerative disorders?
A
Mendelian Genetic Cases
These often have a younger onset
3
Q
What are the two major Neurodegenerative disorders?
A
Dementia
Parkinson’s disease
4
Q
Define Dementia
A
Progressive impairment of multiple domains of cognitive function leading to loss of acquired skills and interference in occupational and social roles
5
Q
Define Parkinson’s
A
A clinical syndrome of bradykinesia + atleast one of:
- Rigidity
- Tremors
- Postural Instability
Caused by progressive loss of dopaminergic neurons in the Substantia Nigra
