Acute Limb Ischaemia Flashcards

1
Q

define acute limb ischaemia

A

sudden decrease in limb perfusion causing a threat to limb viability

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2
Q

causes of acute limb ischaemia

A
embolism
atheroembolism
arterial dissection flap
trauma
extrinsic compression
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3
Q

embolic causes of acute limb ischaemia

A
cardiac
AF
MI
valvular disease
acute thrombosis of popliteal aneurysm
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4
Q

atheroembolic causes of acute limb ischaemia

A

thrombus on atherosclerotic plaques

distant cause

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5
Q

presentation of acute limb ischaemia

A

6P’s

  • pain
  • pallor
  • pulseless
  • perishingly cold
  • paraesthesia
  • paralysis
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6
Q

pain in acute limb ischaemia

A

severe
sudden onset
resistant to analgesia
woody compartment (muscle necrosis- irreversible)

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7
Q

pallor in acute limb ischaemia

A

re-fill with stagnated deoxygenated blood giving a mottled appearance due to occlusions occuring
non-blanching mottling is irreverisble ischaemia

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8
Q

when is a limb not salvageable?

A
fixed mottling
non-blanching
compartment tender/red
paralysis 
>12 hours
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9
Q

signs that indicate partly reversible ischaemia

A

blanching mottling

4-12 hours

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10
Q

signs in a salvageable foot

A

white foot
painful
sensorimotor deficit
0-4 hours

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11
Q

management of acute limb ischaemia

A
  • anticoagulation with LMWH
  • anaesthetic (if anticoagulated patient cannot have regional)
  • surgery
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12
Q

surgical options if limb salvageable

A

embolectomy
thrombolysis
fasciotomies

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13
Q

surgical options if limb unsalvageable

A

palliation

amputation

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14
Q

what is an embolectomy?

A

surgical removal of embolus from inside of the artery using an inflatable balloon (Fogarty balloon) to pull the clot back

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15
Q

what is are fasciotomies?

A

when the limb is successfully reperfused it can cause massive oedema in fascial compartments which need pressure release

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16
Q

what causes reperfusion injury?

A

local tissue oedema (compartment syndrome)

toxins released from ischaemic tissue

17
Q

what toxins are released in reperfusion injury from ischaemic tissue?

A

myoglobin from muscle

K+ and H+ affect cellular environment

18
Q

what can reperfusion injury lead to?

A

SIRS