Flashcards in 11 Deck (23)
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1
FDA approved SSRIs for PTSD
sertraline
paroxetine
2
onset age for bipolar 1 vs 2
1- 18
2- 20s
3
risk of future episodes if first episode is mania vs depression
mania- 70%
depression- 50%
4
Since these type of antidepressants were introduced, studies have shown an increased switch rate & an
increase in the number
of rapid cycling cases
TCAs and SNRIs
5
Of all the antidepresants, using this one appears to carry the least risk
of inducing a manic episode
buproprion
6
meds to treat acute mania
-lithium
-depakote
-carbamazepine
-ziprasidone
-quetiapine
-asenapine
7
meds to treat bipolar maintencane
-lithium
-lamotrigine
-quetiapine
-olanzapine
-abilify
8
meds to treat bipolar depression
-lithium
-lamotrigine
-lorazadone
-quetiapine
-symbyax
9
While often used as an adjunct treatment of major depression,
this SGA is NOT shown to be beneficial in the treatment of bipolar depression
abilify
10
Often this symptom heralds
the onset of a new manic episode
decreased need for sleep
11
The washout period when
switching from an MAOI
to any SSRI is this
2 weeks
12
SSRIs or venlafaxine (effexor) may cause these common side effects which NaSSA’s 5HT3 antagonism may help reduce or remove
GI
13
Onset of therapeutic effect on insomnia and anxiety is typically in this time period for mirtzapeine
immediate
14
Fluoxetine (prozac), paroxetine (paxil), bupropion (wellbutrin), duloxetine (cymbalta) and other medications may increase all TCA’s concentration by
inhibiting this p450 enzyme
2D6
15
Blood levels should be drawn about this many hours after the last dose
12 hrs
16
To confirm therapeutic levels after starting lithium or increasing the dose, a lithium level
should be done after this
number of days
5 days
17
Before starting a male patient
on Divalproex Sodium
(Depakote), these two
lab tests should be done
LFTs and platelets
18
trough levels should be drawn at how many hours of immediate vs extended release of depakote
IR- 12 hrs
ER- 18 hrs
19
Carbamazepine (tegretol) has a
black box warning for these two
rare (~1/100,000 = 0.001%)
but serious side effects on
the hematopoietic system
agranulocytosis & aplastic anemia?
20
Patients who start taking lamotrigine (lamictal) have a this % risk of developing a benign rash
10%
21
This SGA has FDA indication to treat acute mania & must be taken sublingually because if it is swallowed only ~5% will be bioavailable due to 1st pass liver metabolism
asenapine
22
which antipsychotics are available in long acting injectable form
risperidone
palliperodone
olanzapine
abilify
23
