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1

FDA approved SSRIs for PTSD

sertraline
paroxetine

2

onset age for bipolar 1 vs 2

1- 18
2- 20s

3

risk of future episodes if first episode is mania vs depression

mania- 70%
depression- 50%

4

Since these type of antidepressants were introduced, studies have shown an increased switch rate & an
increase in the number
of rapid cycling cases

TCAs and SNRIs

5

Of all the antidepresants, using this one appears to carry the least risk
of inducing a manic episode

buproprion

6

meds to treat acute mania

-lithium
-depakote
-carbamazepine
-ziprasidone
-quetiapine
-asenapine

7

meds to treat bipolar maintencane

-lithium
-lamotrigine
-quetiapine
-olanzapine
-abilify

8

meds to treat bipolar depression

-lithium
-lamotrigine
-lorazadone
-quetiapine
-symbyax

9

While often used as an adjunct treatment of major depression,
this SGA is NOT shown to be beneficial in the treatment of bipolar depression

abilify

10

Often this symptom heralds
the onset of a new manic episode

decreased need for sleep

11

The washout period when
switching from an MAOI
to any SSRI is this

2 weeks

12

SSRIs or venlafaxine (effexor) may cause these common side effects which NaSSA’s 5HT3 antagonism may help reduce or remove

GI

13

Onset of therapeutic effect on insomnia and anxiety is typically in this time period for mirtzapeine

immediate

14

Fluoxetine (prozac), paroxetine (paxil), bupropion (wellbutrin), duloxetine (cymbalta) and other medications may increase all TCA’s concentration by
inhibiting this p450 enzyme

2D6

15

Blood levels should be drawn about this many hours after the last dose

12 hrs

16

To confirm therapeutic levels after starting lithium or increasing the dose, a lithium level
should be done after this
number of days

5 days

17

Before starting a male patient
on Divalproex Sodium
(Depakote), these two
lab tests should be done

LFTs and platelets

18

trough levels should be drawn at how many hours of immediate vs extended release of depakote

IR- 12 hrs
ER- 18 hrs

19

Carbamazepine (tegretol) has a
black box warning for these two
rare (~1/100,000 = 0.001%)
but serious side effects on
the hematopoietic system

agranulocytosis & aplastic anemia?

20

Patients who start taking lamotrigine (lamictal) have a this % risk of developing a benign rash

10%

21

This SGA has FDA indication to treat acute mania & must be taken sublingually because if it is swallowed only ~5% will be bioavailable due to 1st pass liver metabolism

asenapine

22

which antipsychotics are available in long acting injectable form

risperidone
palliperodone
olanzapine
abilify

23

antiemetic medication(s) is/are a D2 blocker(s) and may cause EPS or TD

Prochlorperazine (Compazine)
Metoclopramide (Reglan)
Droperidol (Inapsine)
Promethazine (Phenergan)