Haematology - Microcytic Flashcards

1
Q

Fe dificiency sy

A

Sore red tongue, koilonychia

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2
Q

Fe deficiency ax

A

Blood loss or malabsorption

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3
Q

Iron deficiency mx

A

Oral ferrous sulphate

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4
Q

Normal haem genes

A

2a2b

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5
Q

Alpha thalassamie mx

A

Blood transfusion

Bone marrow transplant can be curative

(single gene effected, both genes is called hydrops fetalis and incompatible with life)

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6
Q

Beta minor px

A

Carrier (1 abnormal, 1 normal)

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7
Q

Beta minor sy

A

Microcytic anaemia

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8
Q

Beta minor mx

A

None

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9
Q

Beta intermediate px

A

2 defective (or 1 defective, 1 deleted)

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10
Q

Beta intermedia mx

A

Blood transfusion

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11
Q

beta major px

A

Two deletions

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12
Q

Beta major sy

A

Severe anaemia and failure to thrive

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13
Q

Thalassaemia sy

A

Anaemia, splenomegaly

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14
Q

Sickle cell sy

A

Bone pain, jaundice, failure to thrive

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15
Q

Sickle cell crises precipitation

A

Infection, dehydration, hypoxia, cold

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16
Q

Sickle cell mx

A

Hydroxycarbamide (prevent crises)