Cephalosporins DI Flashcards

1
Q

3rd generation cephalosporins

A

Ceftazidime, ceftriaxone

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2
Q

4th generation cephalosporin

A

Cefepime

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3
Q

Cephalosporins MoA

A

Same as PCNs! Bind to transpeptidase enzymes in the bacterial cell and disrupt cell wall formation

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4
Q

Ceftazidime and cefepime spectrum of activity

A

+++ against pseudomonas

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5
Q

Ceftazidime side effects

A

Increased LFTs, neutropenia

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6
Q

Cefepime side effects

A

Similar to PCNs

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7
Q

Cephalosporins for proteus mirabilis

A

Cephalexin, cefazolin

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8
Q

1st generation cephalosporins

A

Cephalexin, cefazolin

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9
Q

Cephalosporin for E. coli

A

Cefazolin

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10
Q

Cephalosporin for Klebsiella

A

Cefazolin

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11
Q

Alternate treatment for E. coli

A

Gentamicin

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12
Q

Cephalosporin for H. influenzae

A

Cefoxitin, cefaclor, cefotetan

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13
Q

2nd generation cephalosporins

A

Cefoxitin, cefaclor, cefotetan

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14
Q

Cephalosporin for Moraxella

A

Ceftriaxone

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15
Q

Cephalosporin for serratia marcescens

A

Ceftriaxone and cefepime

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16
Q

Cephalosporin for pseudomonas

A

Cefepime

17
Q

Cephalosporin for acinetobacter

A

Cefepime

18
Q

Cephalosporin for Citrobacter

A

Cefepime

19
Q

Cephalosporin for enterobacter

A

Cefepime

20
Q

Alternate treatment for pseudomonas

A

Tobramycin, ciprofloxacin

21
Q

Alternate treatment for acinetobacter

A

Ceftaroline

22
Q

Alternate treatment for citrobacter

A

Ceftaroline

23
Q

Alternate treatment for enterobacter

A

Ceftaroline