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PHM 603- ID Part 1 > Nitroimidazole DI > Flashcards

Nitroimidazole DI Flashcards

1
Q

Nitroimidazole

A

Metronidazole

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2
Q

Nitroimidazole MoA

A

Reduced to a toxic intermediate that produces damage by interaction with bacterial DNA

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3
Q

Are nitroimidazoles bacteriostatic or bactericidal?

A

Bactericidal

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4
Q

Metronidazole spectrum of activity

A

+++ against gram positive aerobes

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5
Q

Metronidazole side effect

A

Disulfiram reaction, GI intolerance, metallic taste

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PHM 603- ID Part 1 (22 decks)

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