Glycopeptides DI

Question 1

Glycopeptide

Answer 1

Vancomycin

Question 2

Glycopeptide MoA

Answer 2

Bind to the D-alanyl-D-alanine terminal residue in the growing peptidoglycan chain to inhibit cell wall formation

Question 3

Are glycopeptides bacteriostatic or bactericidal?

Answer 3

Bactericidal

Question 4

Vanco spectrum of activity

Answer 4

+++ activity against gram-positive anaerobes, MRSA, enterococcus

++ against MSSA

Question 5

Vanco side effects

Answer 5

Nephrotoxicity, ototoxicity, Red Man Syndrome, neutropenia, rash

Question 6

Vanco is the drug of choice ins what kind of infections?

Answer 6

MRSA