Non-purulent SSTIs

Question 1

Signs of cellulitis/erysipelas

Answer 1

Redness, heat, swollen, painful

Presents as more diffuse across a certain region

Exterior organ involved (skin)

Question 2

Risk factors

Answer 2

Athlete’s foot, dry and fragile skin, obesity, previous skin trauma, previous cellulitis, edema from venous insufficiency

Question 3

Majority of non-purulent SSTIs are caused by what bacteria?

Answer 3

STREP species

Question 4

Subset of severe cellulitis is caused by what bacteria?

Answer 4

Staph aureus

Question 5

Non-purulent SSTI treatment

Answer 5

ABX! Don’t do drainage or cultures unless it’s a severe case

Question 6

Mild non-purulent infection

Answer 6

Infection with no systemic signs

Question 7

Moderate non-purulent infection identification

Answer 7

Very severe clinical/physical presentation or 1 systemic sign

Question 8

Severe non-purulent infection

Answer 8

any 2 SIRS criteria

Question 9

PO vs. IV treatment of non-purulent infection

Answer 9

PO in mild cases, IV in severe but de-escalate to PO when possible

Question 10

PO options for non-purulent infections

Answer 10

Amoxicillin/clav, cephalexin are drugs of choice

Question 11

IV options for strep (non-purulent SSTIs)

Answer 11

Cefazolin, ceftriaxone, clindamycin

Question 12

PO option for people who have a beta-lactam allergy

Answer 12

Clindamycin

Question 13

IV options for people with a PCN allergy

Answer 13

Clindamycin, vanco, linezolid, dapto

Question 14

Non-purulent infection duration of therapy

Answer 14

Mild: 5 days

Moderate-severe: 10-14 days but can be longer in more difficult cases