Looking at cells

Question 1

Immunophenotyping

Answer 1

expression profile of proteins (antigens) on the surface of cells

Question 2

Bio-assay

Answer 2

culture in vitro and show lineage of progeny in different growth conditions

Question 3

List 2 ways of recognising primitive precursors of blood cells? i.e. how to figure out what an earlier stem cell is gonna become

Answer 3

Immunophenotyping,

bio-assay used in path

Question 4

What sites are tested and relevant to investigating blood problems? (5)

Answer 4

peripheral blood, 
bone marrow, 
spleen,
liver, 
lymph nodes

Question 5

Common site for bone marrow aspiration and biopsy

Answer 5

posterior iliac crest

Question 6

Two types of tests done during bone marrow biopsy

Answer 6

take a biopsy - trephine to look at cells in context so look at lump of tissue
syringe of bone marrow - look at individual cells

Question 7

What is blood film assessing?

Answer 7

Cellular morphology