Paeds Anaemia Flashcards
High plateltes why
Upregulation of bone marrow means platelte production also increased
If iron deficiency caused by malabsorpion , what are two other common presentations?
Failure to thrive,
Fatty stools
Physuiological anaemia
Due to the high demands for iron in the growing child demand outstrips intake that would be considered normally, breast milk iron content now too low for needs
How do you treat paediatric iron deficiency anaemia?
Change diet and give iron (sodium feredetate)
Changing breast milk to cow’s milk lessens iron intake as cow’s milk has less iron than breast milk. T/F?
True
How do you assess response of iron treatment in iron defiency anaemia?
Repeat bloods in 3 months usually, sometimes 6 weeks
Common paeds anaemia age?
Age 2 who’ve been changed from breast milk
Globin chain synthesis
Low Hb, Low mcv, High ferritin, High platelets, Inherited as brother with same
What investigation should you do if suspicious of a globin synthesis production problem?
Haemoglobinopathy screen - Separates colour of red cells to screen for haemoglobin a2
Treatment for globin synthesis problem
Blood transufsion to maintain a minimum Hb, usually once a month
To help excrete iron, what is treatment
Under 2 subcut injections,
Over 2 oral tablets
Which organs does iron overload affect?
Heart, liver, brain, spleen, deposits in pituitary gland so failure to thrive in younger people
Complication of regular transfusions?
Iron overload
Annual what to assess for complicatiosn of long term transfusion?
Annual MRI of brain and heart
Why are spherocytes visible on film of peripheral red cell destruction problem
Congenital problem -
