General Phamacology Flashcards
Pharmacology
The study of substances that interact with living systems via chemical processes
Drug
Any substance that produces changes in the body biological function through its chemical action
Sources of drugs
Natural sources
Synthetic sources
Naural sources of dugs examples
- Animal source: insulin
- Plant source: Atropine and Mophine
- MIcroorganism: Antibiotics from fungi like penicillin
Synnthetic drugs examples
Asprin
Paracetamol
Barbiturates
Sulphonamides
Drug-body interactions can be :
- Pharmacokinetics
- Pharmacodynamics
Pharmakokinetics is the action of the ….. on the ……
Action of the BODY on the DRUG
Pharmacokinetics can be:
- Absorption
- Distribution
- Metabolism
- Excretion
Absorption definition
Tansfer of the drug from site of administration to the systemic circulation
Determines the route of admistration
Routes of admistration:
- Oral route
- Sublingual route
- Rectal route
- Parentral route
- Subcutaneous Injection
- Intramuscular Injection
- Intravenous Injection
- Inhalation
- Topical (local) administration
Distribution definition:
It is the process by which the drug leaves the blood stream and enters the tissue
Elimination (fate) of drugs:
Incudes metabolism and excretion
Metabolism definition and main site:
Chemical alteration of the drug in the body
Liver is the main site of drug metabolism
Excretion definition and main site:
The passage out of absorbed drug from the body
Kidney is the main site of drug excretion
Pharmacodynamics is the action of the …. on the ……
The action of the DRUG on the BODY
