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Hospital Based Medicine And Surgery > L17: Lung Cancer > Flashcards

L17: Lung Cancer Flashcards

1
Q

What are the risk factors for lung cancer

A 
Smoking
Passive smoking
Occupational exposure: asbestos 
Family history of lung cancer
Air pollution
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2
Q

What are the 4 main types of bronchial lung cancer

A

Small oat cell carcinoma
Adenocarcinoma
Sqaumous carcinoma large cell carcinoma
Large cell carcinoma

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3
Q

What is malignant mesothelioma

A

Cancer of the lining of the lungs linked to asbestos exposure

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4
Q

What is small cell lung carcinoma

A

Cancer that arises from neuroendocrine cells that produce hormones

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5
Q

What is small cell carcinoma associated with

A

Smoking

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6
Q

What is the prognosis of small cell carcinoma

A

Poor

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7
Q

What are the non small cell carcinoma types

A

Adenocarcinoma
Squamous carcinoma
Large cell carcinoma

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8
Q

Where are adenocarcinoma usually located

A

In the peripheral lung tissue

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9
Q

Which cells do adenocarcinoma arise from

A

Mucous cells in the bronchial epithelium

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10
Q

What is adenocarcinoma associated with

A

non smokers

Asbestos exposure

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11
Q

What is squamous cell carcinoma

A

Found centrally close to large airways and presents with obstructive lesions of the bronchus

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12
Q

What is the differentiation of large cell carcinoma

A

Poorly differentiated

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13
Q

Where can secobdary lung be from

A 
Breast
Bone
Prostate
Colon 
Ovary
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14
Q

What are the signs of lung cancer

A 
Fever
Nausea
Vomiting
Weakness
Cachexia
Haorseness, dysphagia- if there is pressure on the oesophagues
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15
Q

What are the peripheral sings of lung cancer

A

Finger clubbing
Muscle wasting of the hand
Redness in the face due to SVC obstruction

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16
Q

What are the chest signs of lung cancer

A 
Wheeze
Stridor
Consolidation
Pleural effusion
Lung collapse
17
Q

What is a paraneoplastic feature

A

Production of hormones due to cancer leads to associated symptoms

18
Q

What are the paraneoplastic features of squamous cell carcinoma

A

Clubbing
Hyperthyroidism due to ectopic tsh
Hypertrophic pulmonary osteoarthropathy

19
Q

What are the paraneoplastic features in small cell carcinoma

A

ACTH

20
Q

What is a paraneoplastic feature of adenocarcinoma

A

Gynaecomastia

21
Q

What are the investigations of lung cancer

A

Chest xray
Ct scan
Pet ct scan for metasises

22
Q

How do we diagnose the tissue in lung cancer

A 
By biopsy:
Bronchosocpy
EBUS-TBNA
Percutanous needle biopsy
Surgical biopsy
23
Q

What is the staging of lung cancer by

A

TNM

24
Q

What does the management of lung cancer involve

A

Smoking cessation
Chemotherapy
Radiotheroay
Targeted biological therapy

25
Q

What are the complications of lung cancer

A

Superiror vena cava obstruction
Hypercalcaemia
Cerebral metastasis
Spinal cord compression

Hospital Based Medicine And Surgery (30 decks)

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