112114 head and neck path

Question 1

cold sores from what

Answer 1

HSV type I – herpes stomatitis

Question 2

3 M’s for Tzank test for herpes stomatitis

Answer 2

multinucleation
molding
margination

Question 3

squamout papilloma is associated with

Answer 3

low risk subtype HPV

Question 4

precancerous lesions of oral cavity

Answer 4

leukoplakia

erythroplakia (usually associated with epithelial dysplasia)

Question 5

sequence of development of squamous cell carcinoma

Answer 5

hyperplasia
dysplasia
carcinoma

Question 6

epithelial dysplasia

Answer 6

proliferation of immature (basal) cells
loss of cell polarity
increased mitotic figures
variation in nuclear size and shape
hyperchromasia

Question 7

squamous cell carconoma of oral cavity and larynx occurs usually what age?

Answer 7

50-70

Question 8

squamous cell carcinoma of oral cavity and larynx occurs more often in males or females?

Answer 8

males

Question 9

what risk factors are associated with sq cell carcinoma of oral cavity and larynx?

Answer 9

tobacco
alcohol
HPV high risk serotype infection

family hx
erythroplakia

Question 10

histology of sq cell carcinoma

Answer 10

nests with keratin (pink) under basement membrane

Question 11

nonkeratizing sq cell carcinoma-what is it associated with?

Answer 11

HPV high risk types

Question 12

what are Schneiderian papillomas associated with

Answer 12

HPV low risk subtypes

Question 13

what forms circles, rosettes?

Answer 13

olfactory neuroblastoma

Question 14

what are risk factors for nasopharyngeal carcinoma?

Answer 14

geographic-Africa, China

EBV infection

Question 15

most common salivary gland tumor

Answer 15

pleomorphic adenoma

Question 16

pleomorphic adenoma

Answer 16

benign mixed tumor
pleomorphic
adenoma (proliferation of cells-epithelial and myoepithelial)

Question 17

Warthin tumor

Answer 17

microscopy: bilayered oncocytic (pink) epithelial cells and lymphocytes

Question 18

mucoepidermoid carcinoma

Answer 18

mixture of squamoid, mucous, and intermediate cells

Question 19

adenoid cystic carcinoma

Answer 19

microscopy:
perinerual invasion
CRIBRIFORM ARCHITECTURE (swiss cheese like)