Transport of O2 Flashcards

1
Q

Adaptations of Erythocytes (RBCs)

A

Biconcave shape => maximises surface area for gas exchange
Small +flexible to pass through through narrow capillaries
No nucleus => move room to carry respiratory gases
Packed with haemoglobin (HB)

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2
Q

Haemoglobin

A

Protein making up 95% of mass of RBC + is means of transport of oxygen around the body

Made of 4 polypeptide chains each bonded to 1 haem group

Each haem group contain 1 O molecule so ecah HB carries 4 Os max

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3
Q

Oxygen in the lungs diffuse into RBCs

A

O2 diffuses into blood plasma - down conc gradient to RBC - and binds to HB

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4
Q

Oxygen in respiring tissues

A

Oxygen dissociates from oxyhaemoglobin and diffuses out of erythocytes to respiring cells

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5
Q

Effect of O2 conc on diffusion

A

O binds to HB when O is at high conc + dissociates from HB at low conc

=> conc of gas in a mixture of gases can be qualified as partial pressure

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6
Q

When oxygen dissociation curve shifts to left (e.g. fetal HB)

A

The <= the curve, the more readily the pigment associates with O2 but the less readily it dissociates

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7
Q

When oxygen dissociation curves shifts to the right

A

The more => the curve the less readily the pigment asociates w/ O2 but the less readily it dissociates

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