Pupil disorders Flashcards

1
Q

Simulation of circular muscles (iris) that constrict the pupil vs dilator muscles that dilate

A

PNS (CN3) —> Ach

SNS —> adrenaline

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2
Q

How can anterior uveitis change the pupil shape

A

Cause adhesions in iris (scar tissues)

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3
Q

Acute angle closure glaucoma on pupil shape

A

Vertical oval (ischaemic damage)

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4
Q

Rubeosis iridis is … it can cause … and is often associated with

A
  • iris neovascularisation
  • discord lens shape
  • poorly controlled DM, htn
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5
Q

What is coloboma and what can it cause

A
  • congenital eye malformation

- hole in iris —> irregular pupil shape

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6
Q

Tadpole pupil is … and is associated with …

A
  • spasm in iris —> misshapen pupil

- migraines

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7
Q

Causes of mydriasis (dilated pupil)

A
  • third nerve palsy
  • holmes-aide syndrome
  • raised IC pressure
  • congenital
  • trauma
  • stimulants (cocaine)
  • anticholinergics
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8
Q

Causes of miosis (constricted pupil)

A
  • Horner syndrome
  • cluster headache
  • Argyll-Robertson pupil
  • opiates
  • nicotine
  • pilocarpine
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9
Q

Innervations of third nerve that lead to the abnormalities found in its palsy

A
  • extraocular muscles except LR & SO —> divergent strabismus
  • levator palperbae superioris —> ptosis
  • PS innervation to iris sphincter muscles —> dilated fixed pupil
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10
Q

Vascular (surgical third) causes of CNIII palsy due to its course through cavernous sinus

A
  • cavernous sinus thrombosis

- PCA aneurysm

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11
Q

CN3 palsy with sparing of PS fibres suggests what type of cause

A

Microvascular

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12
Q

Are light and accommodation reflexes affected in Horner syndrome

A

No

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13
Q

Central lesions cause anhidrosis in

A
  • arm
  • trunk
  • face
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14
Q

Pre-ganglionic lesions cause anhidrosis in

A

Face

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15
Q

Post-ganglionic lesions cause anhidrosis in

A

Nowhere

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16
Q

4Ss causes of central lesions

A

Stroke
MS
Swelling (tumour)
Syringomyelia

17
Q

4Ts causes of pre-ganglionic lesions

A

Tumour (pancoast)
Trauma
Thyroidectomy
Top rib

18
Q

4Cs causes of post-ganglionic lesions

A

Carotid aneurysm
Carotid artery dissection
Cavernous sinus thrombosis
Cluster headache

19
Q

Congenital Horner’s is associated with

A

Heterochromia

20
Q

How do cocaine eye drops test for horners (also adrenalin eye drops)

A

Cocaine blocks adrenaline re-uptake —> + adrenaline present normally —> no adrenaline released by nerves in CNIII palsy —> no reaction

21
Q

Damage to the post-ganglionic PS fibres in Holmes Adie pupil lead to

A

Unilateral dilated pupil sluggish to react to light with slow dilation following constriction

22
Q

Holmes Adie syndrome

A

Holmes adie pupil + absent knee/ankle reflexes

23
Q

Argyll-Robertson pupil is specific to

A

Neurosyphillis

24
Q

Define Argyll-Robertson pupil

A

Constricted pupil, accommodates when focusing near objects, does not react to light